Ubiquitin-Conjugating Enzyme E2K (UBE2K) Peptide
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- Target See all UBE2K products
- UBE2K (Ubiquitin-Conjugating Enzyme E2K (UBE2K))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-HIP2 antibody (Catalog #: ARP43048_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- UBE2K (Ubiquitin-Conjugating Enzyme E2K (UBE2K))
- Synonyms
- E2-25K Peptide, HIP2 Peptide, HYPG Peptide, LIG Peptide, UBC1 Peptide, E2-25k Peptide, Hip2 Peptide, Hypg Peptide, Lig Peptide, e2-25k Peptide, hip2 Peptide, hypg Peptide, lig Peptide, AW492011 Peptide, D5Ertd601e Peptide, ube2k Peptide, zgc:103472 Peptide, zgc:110791 Peptide, ubiquitin conjugating enzyme E2 K Peptide, ubiquitin-conjugating enzyme E2K Peptide, ubiquitin conjugating enzyme E2 K S homeolog Peptide, ubiquitin-conjugating enzyme E2Kb (UBC1 homolog, yeast) Peptide, ubiquitin-conjugating enzyme E2Ka (UBC1 homolog, yeast) Peptide, UBE2K Peptide, Ube2k Peptide, ube2k.S Peptide, ube2k Peptide, ube2kb Peptide, ube2ka Peptide
- Background
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HIP2 belongs to the ubiquitin-conjugating enzyme family. It binds selectively to a large region at the N terminus of huntingtin. This interaction is not influenced by the length of the huntingtin polyglutamine tract. This protein has been implicated in the degradation of huntingtin and suppression of apoptosis.The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. It binds selectively to a large region at the N terminus of huntingtin. This interaction is not influenced by the length of the huntingtin polyglutamine tract. This protein has been implicated in the degradation of huntingtin and suppression of apoptosis.
Alias Symbols: HYPG, LIG, UBE2K, HIP2, UBC1, E2-25K
Protein Interaction Partner: HTT,HTT,NEDD8,NFKB1,PIAS4,TP53,TRIM3,DDX58,DSTYK,HTT,RNF2,UBE2I
Protein Size: 200 - Molecular Weight
- 22 kDa
- Gene ID
- 3093
- NCBI Accession
- NM_005339, NP_005330
- UniProt
- P61086
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