Mediator Complex Subunit 21 (MED21) (N-Term) Peptide
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- Target See all MED21 products
- MED21 (Mediator Complex Subunit 21 (MED21))
- Protein Region
- N-Term
- Origin
- Human, Mouse
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)
- Sequence
- FCNAIGVLQQ CGPPASFSNI QTAINKDQPA NPTEEYAQLF AALIARTAKD
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-Med21 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- MED21 (Mediator Complex Subunit 21 (MED21))
- Synonyms
- SURB7 Peptide, fk48d02 Peptide, surb7 Peptide, wu:fk48d02 Peptide, zgc:56532 Peptide, SRB7 Peptide, hSrb7 Peptide, 0610007L03Rik Peptide, AI449604 Peptide, D19234 Peptide, D6Ertd782e Peptide, Srb7 Peptide, Surb7 Peptide, T4B21.8 Peptide, T4B21_8 Peptide, mediator 21 Peptide, mediator complex subunit 21 Peptide, Med21p Peptide, mediator 21 Peptide, MED21 Peptide, med21 Peptide, Med21 Peptide
- Background
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Med21 is a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Alias Symbols: 0610007L03Rik, AI449604, D19234, D6Ertd782e, Srb7, Surb7
Protein Interaction Partner: Nfe2
Protein Size: 144 - Molecular Weight
- 15 kDa
- Gene ID
- 108098
- NCBI Accession
- NM_025315, NP_079591
- UniProt
- Q9CQ39
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