Mediator Complex Subunit 21 (MED21) (N-Term) Peptide
Quick Overview for Mediator Complex Subunit 21 (MED21) (N-Term) Peptide (ABIN979944)
Target
Origin
Source
Application
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Protein Region
- N-Term
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Sequence
- FCNAIGVLQQ CGPPASFSNI QTAINKDQPA NPTEEYAQLF AALIARTAKD
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-Med21 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MED21 (Mediator Complex Subunit 21 (MED21))
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Background
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Med21 is a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Alias Symbols: 0610007L03Rik, AI449604, D19234, D6Ertd782e, Srb7, Surb7
Protein Interaction Partner: Nfe2
Protein Size: 144 -
Molecular Weight
- 15 kDa
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Gene ID
- 108098
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NCBI Accession
- NM_025315, NP_079591
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UniProt
- Q9CQ39
Target
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