Mediator Complex Subunit 21 (MED21) Peptide
MED21
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN979945
$160.46
Plus shipping costs $50.00
100 μg
Shipping to:
United States
Delivery in 11 to 17 Business Days
Quick Overview for Mediator Complex Subunit 21 (MED21) Peptide (ABIN979945)
Target
MED21
(Mediator Complex Subunit 21 (MED21))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
-
-
Characteristics
- This is a synthetic peptide designed for use in combination with anti-MED21 antibody (Catalog #: ARP37735_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
Purification
- Purified
-
-
-
-
Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Concentration
- 1 mg/mL
-
Buffer
- Final peptide concentration is 1 mg/mL in PBS.
-
Handling Advice
- Avoid repeated freeze-thaw cycles.
-
Storage
- -20 °C
-
Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- MED21 (Mediator Complex Subunit 21 (MED21))
-
Background
-
MED21 belongs to the Mediator complex subunit 21 family. It is the component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Alias Symbols: SRB7, SURB7
Protein Interaction Partner: CDKN1A,TFF1,THRA,THRB,BRCA1,BTF3,CDK8,CDK9,POLR2A,TCEB3,TFG,THRA,THRB,BRCA1,CDK7,CDK8,CREBBP,ESR1,ESR2,GTF2B,GTF2E1,GTF2F1,GTF2H4,HNF4A,KAT2B,MED1,MED10,MED14,MED18,MED19,MED26,MED28,MED29,MED30,MED6,MED9,POLR2A,PPARGC1A,SMARCB1,TCERG1,THRA,VDR
Protein Size: 144 -
Molecular Weight
- 15 kDa
-
Gene ID
- 9412
-
NCBI Accession
- NM_004264, NP_004255
-
UniProt
- Q13503
Target
-
You are here:
