Mediator Complex Subunit 21 (MED21) Peptide
MED21
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all MED21 products
- MED21 (Mediator Complex Subunit 21 (MED21))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-MED21 antibody (Catalog #: ARP37735_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- MED21 (Mediator Complex Subunit 21 (MED21))
- Synonyms
- SURB7 Peptide, fk48d02 Peptide, surb7 Peptide, wu:fk48d02 Peptide, zgc:56532 Peptide, SRB7 Peptide, hSrb7 Peptide, 0610007L03Rik Peptide, AI449604 Peptide, D19234 Peptide, D6Ertd782e Peptide, Srb7 Peptide, Surb7 Peptide, T4B21.8 Peptide, T4B21_8 Peptide, mediator 21 Peptide, mediator complex subunit 21 Peptide, Med21p Peptide, mediator 21 Peptide, MED21 Peptide, med21 Peptide, Med21 Peptide
- Background
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MED21 belongs to the Mediator complex subunit 21 family. It is the component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Alias Symbols: SRB7, SURB7
Protein Interaction Partner: CDKN1A,TFF1,THRA,THRB,BRCA1,BTF3,CDK8,CDK9,POLR2A,TCEB3,TFG,THRA,THRB,BRCA1,CDK7,CDK8,CREBBP,ESR1,ESR2,GTF2B,GTF2E1,GTF2F1,GTF2H4,HNF4A,KAT2B,MED1,MED10,MED14,MED18,MED19,MED26,MED28,MED29,MED30,MED6,MED9,POLR2A,PPARGC1A,SMARCB1,TCERG1,THRA,VDR
Protein Size: 144 - Molecular Weight
- 15 kDa
- Gene ID
- 9412
- NCBI Accession
- NM_004264, NP_004255
- UniProt
- Q13503
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