Protein Phosphatase 1, Regulatory Subunit 8 (PPP1R8) (Middle Region) Peptide
PPP1R8
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all PPP1R8 products
- PPP1R8 (Protein Phosphatase 1, Regulatory Subunit 8 (PPP1R8))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-PPP1R8 antibody (Catalog #: ARP40411_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PPP1R8 (Protein Phosphatase 1, Regulatory Subunit 8 (PPP1R8))
- Synonyms
- ARD-1 Peptide, ARD1 Peptide, NIPP-1 Peptide, NIPP1 Peptide, PRO2047 Peptide, 6330548N22Rik Peptide, AU044684 Peptide, PPP1R8 Peptide, ard-1 Peptide, ard1 Peptide, nipp-1 Peptide, nipp1 Peptide, ppp1r8 Peptide, si:ch211-206a7.1 Peptide, protein phosphatase 1 regulatory subunit 8 Peptide, protein phosphatase 1, regulatory subunit 8 Peptide, protein phosphatase 1, regulatory (inhibitor) subunit 8 Peptide, protein phosphatase 1, regulatory subunit 8b Peptide, protein phosphatase 1 regulatory subunit 8 L homeolog Peptide, protein phosphatase 1, regulatory subunit 8a Peptide, protein phosphatase 1 regulatory subunit 8 S homeolog Peptide, PPP1R8 Peptide, Ppp1r8 Peptide, ppp1r8b Peptide, ppp1r8.L Peptide, ppp1r8a Peptide, ppp1r8.S Peptide
- Background
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This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA.This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA. This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA.
Alias Symbols: ARD-1, ARD1, NIPP-1, NIPP1, PRO2047
Protein Interaction Partner: C14orf1,C7orf64,CDC5L,CRMP1,CSNK2A1,CSNK2A2,EED,GBP2,HDAC2,LYN,MELK,PPP1CA,PPP1CC,PRKACA,SETDB1,SF3B1,STC2,C14orf1,C7orf64,CRMP1,EED,GBP2,HDAC2,LYN,NME2,PPP1CA,PPP1CB,PPP1CC,PRKACA,SETDB1,SF3B1,STC2
Protein Size: 351 - Molecular Weight
- 38 kDa
- Gene ID
- 5511
- NCBI Accession
- NM_014110, NP_054829
- UniProt
- Q12972
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