Protein Phosphatase 1, Regulatory Subunit 8 (PPP1R8) (N-Term) Peptide
PPP1R8
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN982116
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100 μg
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Quick Overview for Protein Phosphatase 1, Regulatory Subunit 8 (PPP1R8) (N-Term) Peptide (ABIN982116)
Target
PPP1R8
(Protein Phosphatase 1, Regulatory Subunit 8 (PPP1R8))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- DKLIEKLIID EKKYYLFGRN PDLCDFTIDH QSCSRVHAAL VYHKHLKRVF
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-PPP1R8 Antibody(ARP40754_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PPP1R8 (Protein Phosphatase 1, Regulatory Subunit 8 (PPP1R8))
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Background
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This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA.This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA.
Alias Symbols: ARD-1, ARD1, NIPP-1, NIPP1, PRO2047
Protein Interaction Partner: C14orf1,C7orf64,CDC5L,CRMP1,CSNK2A1,CSNK2A2,EED,GBP2,HDAC2,LYN,MELK,PPP1CA,PPP1CC,PRKACA,SETDB1,SF3B1,STC2,C14orf1,C7orf64,CRMP1,EED,GBP2,HDAC2,LYN,NME2,PPP1CA,PPP1CB,PPP1CC,PRKACA,SETDB1,SF3B1,STC2
Protein Size: 351 -
Molecular Weight
- 38 kDa
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Gene ID
- 5511
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NCBI Accession
- NM_014110, NP_054829
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UniProt
- Q12972
Target
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