Ubiquitin-Conjugating Enzyme E2N (UBE2N) Peptide
Quick Overview for Ubiquitin-Conjugating Enzyme E2N (UBE2N) Peptide (ABIN985834)
Target
Origin
Source
Application
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-UBE2N antibody (Catalog #: ARP33126_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- UBE2N (Ubiquitin-Conjugating Enzyme E2N (UBE2N))
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Background
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UBE2N encodes a member of the E2 ubiquitin-conjugating enzyme family. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. Studies in mouse suggest that this protein plays a role in DNA postreplication repair.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Studies in mouse suggest that this protein plays a role in DNA postreplication repair.
Alias Symbols: MGC131857, MGC8489, UBC13, UbcH-ben
Protein Interaction Partner: BCL10,AURKA,BCL10,RNF11,RNF128,SLC2A4,TMEM189-UBE2V1,TRAF6,UBB,UBE2V1,UBE2V2,AURKA,CHUK,CNTN2,HLTF,IL1B,MMZ1,OTUB1,RNF128,SLX5,SLX8,STAMBPL1,TNF,TP53,TRAF2,TRAF6,TRIM32,UBE2V1,UEV1D-4
Protein Size: 152 -
Molecular Weight
- 17 kDa
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Gene ID
- 7334
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NCBI Accession
- NM_003348, NP_003339
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UniProt
- P61088
Target
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