Tyrosyl-tRNA Synthetase (Yars) Peptide
Yars
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all YARS (Yars) products
- YARS (Yars) (Tyrosyl-tRNA Synthetase (Yars))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-YARS antibody (Catalog #: ARP40471_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- YARS (Yars) (Tyrosyl-tRNA Synthetase (Yars))
- Synonyms
- CMTDIC Peptide, TYRRS Peptide, YRS Peptide, YTS Peptide, AL024047 Peptide, AU018965 Peptide, cb204 Peptide, wu:fk52b08 Peptide, YARS Peptide, cmtdic Peptide, tyrrs Peptide, yrs Peptide, yts Peptide, CG4561 Peptide, Dmel\\CG4561 Peptide, TyrRS Peptide, anon-EST:Posey261 Peptide, dYARS Peptide, GB10789 Peptide, tyrosyl-tRNA synthetase Peptide, tyrosyl-tRNA synthetase L homeolog Peptide, tyrosyl-tRNA synthetase, putative Peptide, tyrosine--tRNA ligase Peptide, Tyrosyl-tRNA synthetase Peptide, tyrosine--tRNA ligase, cytoplasmic Peptide, YARS Peptide, Yars Peptide, yars Peptide, yars.L Peptide, MAL8P1.125 Peptide, MEFER_RS04475 Peptide, TyrRS Peptide, LOC413909 Peptide, LOC100163888 Peptide, LOC100282315 Peptide
- Background
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Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Tyrosyl-tRNA synthetase belongs to the class I tRNA synthetase family. Cytokine activities have also been observed for the human tyrosyl-tRNA synthetase, after it is split into two parts, an N-terminal fragment that harbors the catalytic site and a C-terminal fragment found only in the mammalian enzyme. The N-terminal fragment is an interleukin-8-like cytokine, whereas the released C-terminal fragment is an EMAP II-like cytokine.Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Tyrosyl-tRNA synthetase belongs to the class I tRNA synthetase family. Cytokine activities have also been observed for the human tyrosyl-tRNA synthetase, after it is split into two parts, an N-terminal fragment that harbors the catalytic site and a C-terminal fragment found only in the mammalian enzyme. The N-terminal fragment is an interleukin-8-like cytokine, whereas the released C-terminal fragment is an EMAP II-like cytokine.
Alias Symbols: YRS, YTS, TYRRS, CMTDIC
Protein Interaction Partner: ELANE,ARF6,EIF1B,EIF6,SAP18
Protein Size: 528 - Molecular Weight
- 58 kDa
- Gene ID
- 8565
- NCBI Accession
- NM_003680, NP_003671
- UniProt
- P54577
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