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Tyrosyl-tRNA Synthetase (Yars) Peptide

Yars Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN986283
  • Target See all YARS (Yars) products
    YARS (Yars) (Tyrosyl-tRNA Synthetase (Yars))
    Origin
    Human
    Source
    • 4
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-YARS antibody (Catalog #: ARP40472_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    YARS (Yars) (Tyrosyl-tRNA Synthetase (Yars))
    Synonyms
    CMTDIC Peptide, TYRRS Peptide, YRS Peptide, YTS Peptide, AL024047 Peptide, AU018965 Peptide, cb204 Peptide, wu:fk52b08 Peptide, YARS Peptide, cmtdic Peptide, tyrrs Peptide, yrs Peptide, yts Peptide, CG4561 Peptide, Dmel\\CG4561 Peptide, TyrRS Peptide, anon-EST:Posey261 Peptide, dYARS Peptide, GB10789 Peptide, tyrosyl-tRNA synthetase Peptide, tyrosyl-tRNA synthetase L homeolog Peptide, tyrosyl-tRNA synthetase, putative Peptide, tyrosine--tRNA ligase Peptide, Tyrosyl-tRNA synthetase Peptide, tyrosine--tRNA ligase, cytoplasmic Peptide, YARS Peptide, Yars Peptide, yars Peptide, yars.L Peptide, MAL8P1.125 Peptide, MEFER_RS04475 Peptide, TyrRS Peptide, LOC413909 Peptide, LOC100163888 Peptide, LOC100282315 Peptide
    Background
    Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Tyrosyl-tRNA synthetase belongs to the class I tRNA synthetase family. Cytokine activities have also been observed for the human tyrosyl-tRNA synthetase, after it is split into two parts, an N-terminal fragment that harbors the catalytic site and a C-terminal fragment found only in the mammalian enzyme. The N-terminal fragment is an interleukin-8-like cytokine, whereas the released C-terminal fragment is an EMAP II-like cytokine.Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Tyrosyl-tRNA synthetase belongs to the class I tRNA synthetase family. Cytokine activities have also been observed for the human tyrosyl-tRNA synthetase, after it is split into two parts, an N-terminal fragment that harbors the catalytic site and a C-terminal fragment found only in the mammalian enzyme. The N-terminal fragment is an interleukin-8-like cytokine, whereas the released C-terminal fragment is an EMAP II-like cytokine.Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Tyrosyl-tRNA synthetase belongs to the class I tRNA synthetase family. Cytokine activities have also been observed for the human tyrosyl-tRNA synthetase, after it is split into two parts, an N-terminal fragment that harbors the catalytic site and a C-terminal fragment found only in the mammalian enzyme. The N-terminal fragment is an interleukin-8-like cytokine, whereas the released C-terminal fragment is an EMAP II-like cytokine. Sequence Note: The RefSeq transhttp://www.ncbi.nlm.nih.gov/projects/locusXref/oho.cgi?server= REFTRACK&frm=0x66adf650&appid=0&evId=1&evIntpar=8565&evStrpar=&frmA n=EditApp LocusXref: edit YARS(8565)cript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Alias Symbols: CMTDIC, TYRRS, YRS, YTS

    Protein Interaction Partner: ELANE,ARF6,EIF1B,EIF6,SAP18

    Protein Size: 528
    Molecular Weight
    59 kDa
    Gene ID
    8565
    NCBI Accession
    NM_003680, NP_003671
    UniProt
    P54577
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