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PHC2 Products

(Polyhomeotic Homolog 2 (Drosophila) (PhC2))

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In Drosophila melanogaster, the 'Polycomb' group (PcG) of genes are part of a cellular memory system that is responsible for the stable inheritance of gene activity. PcG proteins form a large multimeric, chromatin-associated protein complex. The protein encoded by this gene has homology to the Drosophila PcG protein 'polyhomeotic' (Ph) and is known to heterodimerize with EDR1 and colocalize with BMI1 in interphase nuclei of human cells. The specific function in human cells has not yet been determined. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Featured PHC2 Categories

PHC2 Antibodies

High quality antibodies with extensive validation data.

PHC2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PHC2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN515167
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN947820
Quantity 100 μg
Datasheet Datasheet
Reactivity Bat, Cow, Dog, Guinea Pig, Horse, Human, Monkey, Mouse, Rabbit, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN6744909
Quantity 100 μL
Datasheet Datasheet

Recommended PHC2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6234235
Quantity 96 tests
Datasheet Datasheet

Recommended PHC2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124511
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1314867
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1314869
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our PHC2 products

Takada, Isono, Shinga, Turner, Kitamura, Ohara, Watanabe, Singh, Kamijo, Jenuwein, Burgoyne, Koseki: "Mammalian Polycomb Scmh1 mediates exclusion of Polycomb complexes from the XY body in the pachytene spermatocytes." in: Development (Cambridge, England), Vol. 134, Issue 3, pp. 579-90, (2007) (PubMed).

Isono, Fujimura, Shinga, Yamaki, O-Wang, Takihara, Murahashi, Takada, Mizutani-Koseki, Koseki: "Mammalian polyhomeotic homologues Phc2 and Phc1 act in synergy to mediate polycomb repression of Hox genes." in: Molecular and cellular biology, Vol. 25, Issue 15, pp. 6694-706, (2005) (PubMed).

Synonyms and alternative names related to PHC2

polyhomeotic homolog 2 L homeolog (phc2.L), polyhomeotic homolog 2 (PHC2), polyhomeotic-like 2 (Drosophila) (Phc2), polyhomeotic homolog 2a (Drosophila) (phc2a), A3galt2, AA415044, cb218, D4Ertd810e, D130050K19Rik, EDR2, Edr2, edr2, HPH2, id:ibd2745, id:ibd5044, Mph2, p36, PH2, ph2, ph2alpha, ph2beta, ph2[a], ph2[b], phc2, wu:fb98c05, wu:fc96f07, zgc:100775, zgc:123102

Protein level used designations for PHC2

  • polyhomeotic-like 2
  • polyhomeotic-like protein 2
  • early development regulator 2 (homolog of polyhomeotic 2)
  • early development regulatory protein 2
  • polyhomeotic 2
  • early development regulator 2
  • polyhomeotic 2 protein
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