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Phosphatidylinositol Binding clathrin Assembly Protein Proteins

(Phosphatidylinositol Binding clathrin Assembly Protein (PICALM))
This gene encodes a clathrin assembly protein, which recruits clathrin and adaptor protein complex 2 (AP2) to cell membranes at sites of coated-pit formation and clathrin-vesicle assembly. The protein may be required to determine the amount of membrane to be recycled, possibly by regulating the size of the clathrin cage. The protein is involved in AP2-dependent clathrin-mediated endocytosis at the neuromuscular junction. A chromosomal translocation t(10\;11)(p13\;q14) leading to the fusion of this gene and the MLLT10 gene is found in acute lymphoblastic leukemia, acute myeloid leukemia and malignant lymphomas. The polymorphisms of this gene are associated with the risk of Alzheimer disease. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011].
PICALM Protein (AA 2-660) (His tag) PICALM Protein (AA 2-660) (His tag) PICALM Protein (AA 2-660) (His tag) (ABIN3135908)

Crystallography grade PICALM Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys

PICALM Protein (AA 2-652) (His tag) PICALM Protein (AA 2-652) (His tag) PICALM Protein (AA 2-652) (His tag) (ABIN3086159)

Crystallography grade PICALM Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys

PICALM Protein (AA 1-610) (GST tag) PICALM Protein (AA 1-610) (GST tag) PICALM Protein (AA 1-610) (GST tag) (ABIN1315001)

PICALM Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA

Phosphatidylinositol Binding clathrin Assembly Protein Proteins by Grade

Find Phosphatidylinositol Binding clathrin Assembly Protein Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

Phosphatidylinositol Binding clathrin Assembly Protein Proteins by Origin

Find Phosphatidylinositol Binding clathrin Assembly Protein Proteins for a variety of species such as anti-Human Phosphatidylinositol Binding clathrin Assembly Protein, anti-Mouse Phosphatidylinositol Binding clathrin Assembly Protein, anti-Rat Phosphatidylinositol Binding clathrin Assembly Protein. The species listed below are among those available. Click on a link to go to the corresponding products.

Phosphatidylinositol Binding clathrin Assembly Protein Proteins by Source

Here you will find Phosphatidylinositol Binding clathrin Assembly Protein Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

Phosphatidylinositol Binding clathrin Assembly Protein Proteins by Protein Type

Here you can find Phosphatidylinositol Binding clathrin Assembly Protein Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

Phosphatidylinositol Binding clathrin Assembly Protein Proteins by Application

Find Phosphatidylinositol Binding clathrin Assembly Protein Proteins validated for a specific application such as ELISA, WB, SDS, Crys. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular Phosphatidylinositol Binding clathrin Assembly Protein Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3135908
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3086159
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1315001
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
  • (1)
Cat. No. ABIN2728884
Quantity 20 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7408408
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Yeast
Validations
Cat. No. ABIN1475689
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our Phosphatidylinositol Binding clathrin Assembly Protein Proteins

Zhao, Sagare, Ma, Halliday, Kong, Kisler, Winkler, Ramanathan, Kanekiyo, Bu, Owens, Rege, Si, Ahuja, Zhu, Miller, Schneider, Maeda, Maeda, Sugawara, Ichida, Zlokovic: "Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance." in: Nature neuroscience, Vol. 18, Issue 7, pp. 978-87, (2015) (PubMed).

Baig, Joseph, Tayler, Abraham, Owen, Williams, Kehoe, Love: "Distribution and expression of picalm in Alzheimer disease." in: Journal of neuropathology and experimental neurology, Vol. 69, Issue 10, pp. 1071-7, (2010) (PubMed).

Aliases for Phosphatidylinositol Binding clathrin Assembly Protein Proteins

leucine aminopeptidase 3 (LAP3) Proteins
phosphatidylinositol binding clathrin assembly protein (PICALM) Proteins
phosphatidylinositol binding clathrin assembly protein (Picalm) Proteins
si:ch211-200p22.4 (si:ch211-200p22.4) Proteins
CALM Proteins
Calm Proteins
CLTH Proteins
fit-1 Proteins
fit1 Proteins
LAP Proteins
LAP-3 Proteins
mKIAA4114 Proteins
PAP180 Proteins
PEPS Proteins
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