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PPP1R8 Products

(Protein Phosphatase 1, Regulatory Subunit 8 (PPP1R8))

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This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA. [provided by RefSeq, Jul 2008].

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Featured PPP1R8 Categories

PPP1R8 Antibodies

High quality antibodies with extensive validation data.

PPP1R8 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PPP1R8 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (7)
Cat. No. ABIN519112
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (4)
Cat. No. ABIN7161805
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IP
Validations
  • (4)
Cat. No. ABIN519111
Quantity 100 μg
Datasheet Datasheet

Recommended PPP1R8 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124669
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1316004
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1316003
Quantity 25 μg
Datasheet Datasheet

Latest Publications for our PPP1R8 products

Nuytten, Beke, Van Eynde, Ceulemans, Beullens, Van Hummelen, Fuks, Bollen: "The transcriptional repressor NIPP1 is an essential player in EZH2-mediated gene silencing." in: Oncogene, Vol. 27, Issue 10, pp. 1449-60, (2008) (PubMed).

Beullens, Bollen: "The protein phosphatase-1 regulator NIPP1 is also a splicing factor involved in a late step of spliceosome assembly." in: The Journal of biological chemistry, Vol. 277, Issue 22, pp. 19855-60, (2002) (PubMed).

Synonyms and alternative names related to PPP1R8

protein phosphatase 1 regulatory subunit 8 (PPP1R8), protein phosphatase 1, regulatory subunit 8 (Ppp1r8), protein phosphatase 1, regulatory (inhibitor) subunit 8 (Ppp1r8), protein phosphatase 1, regulatory subunit 8b (ppp1r8b), protein phosphatase 1 regulatory subunit 8 L homeolog (ppp1r8.L), protein phosphatase 1 regulatory subunit 8 (Ppp1r8), protein phosphatase 1, regulatory subunit 8a (ppp1r8a), protein phosphatase 1 regulatory subunit 8 S homeolog (ppp1r8.S), 6330548N22Rik, ARD-1, ard-1, ARD1, ard1, AU044684, NIPP-1, nipp-1, NIPP1, nipp1, PPP1R8, ppp1r8, PRO2047, si:ch211-206a7.1

Protein level used designations for PPP1R8

  • RNase E
  • activator of RNA decay
  • nuclear inhibitor of protein phosphatase 1
  • nuclear inhibitor of protein phosphatase-1 alpha
  • nuclear subunit of PP-1
  • protein phosphatase 1 regulatory subunit 8
  • protein phosphatase 1, regulatory (inhibitor) subunit 8
  • NIPP-1
  • protein phosphatase 1 regulatory inhibitor subunit 8
  • protein phosphatase 1, regulatory inhibitor subunit 8
  • uncharacterized protein LOC799896
  • protein phosphatase 1, regulatory (inhibitor) subunit 8a
  • protein phosphatase 1, regulatory subunit 8a
  • protein phosphatase 1 regulatory subunit 8 S homeolog
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