PPP2R1A Products
(Protein Phosphatase 2, Regulatory Subunit A, alpha (PPP2R1A))
Categories
This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes an alpha isoform of the constant regulatory subunit A. Alternatively spliced transcript variants have been described. [provided by RefSeq, Apr 2010].
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Featured PPP2R1A Categories
PPP2R1A Antibodies
High quality antibodies with extensive validation data.
PPP2R1A ELISA Kits
Reliable ELISA kits for a wide range of species.
PPP2R1A Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PPP2R1A Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
WB, IF, IP, IHC (p), ICC
Validations
- (1)
- (4)
Cat. No.
ABIN2855322
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, PLA
Validations
- (3)
Cat. No.
ABIN519115
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Drosophila melanogaster, Human, Monkey, Mouse, Rat
Application
WB, IF, FACS
Validations
- (3)
Cat. No.
ABIN354403
Quantity
100 μL
Datasheet
Datasheet
Recommended PPP2R1A ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6971299
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6231881
Quantity
96 tests
Datasheet
Datasheet
Recommended PPP2R1A Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
Cat. No.
ABIN1316014
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7124672
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3087925
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our PPP2R1A products
: "PP2A Deficiency Enhances Carcinogenesis of Lgr5+ Intestinal Stem Cells Both in Organoids and In Vivo." in: Cells, Vol. 9, Issue 1, (2020) (PubMed).: "Clinicopathological effects of protein phosphatase 2, regulatory subunit A, alpha mutations in gastrointestinal stromal tumors." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 29, Issue 11, pp. 1424-1432, (2016) (PubMed).
: "PR65A phosphorylation regulates PP2A complex signaling." in: PLoS ONE, Vol. 9, Issue 1, pp. e85000, (2014) (PubMed).
: "Frequent mutations of chromatin remodeling gene ARID1A in ovarian clear cell carcinoma." in: Science (New York, N.Y.), Vol. 330, Issue 6001, pp. 228-31, (2010) (PubMed).
: "Live-cell imaging RNAi screen identifies PP2A-B55alpha and importin-beta1 as key mitotic exit regulators in human cells." in: Nature cell biology, Vol. 12, Issue 9, pp. 886-93, (2010) (PubMed).
: "Protein phosphatase 2A subunit gene haplotypes and proliferative breast disease modify breast cancer risk." in: Cancer, Vol. 116, Issue 1, pp. 8-19, (2010) (PubMed).
: "Hypoxia-activated Smad3-specific dephosphorylation by PP2A." in: The Journal of biological chemistry, Vol. 285, Issue 6, pp. 3740-9, (2010) (PubMed).
: "HUNK suppresses metastasis of basal type breast cancers by disrupting the interaction between PP2A and cofilin-1." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 6, pp. 2622-7, (2010) (PubMed).
: "A nonhomologous end-joining pathway is required for protein phosphatase 2A promotion of DNA double-strand break repair." in: Neoplasia (New York, N.Y.), Vol. 11, Issue 10, pp. 1012-21, (2009) (PubMed).
: "Direct binding of PP2A to Sprouty2 and phosphorylation changes are a prerequisite for ERK inhibition downstream of fibroblast growth factor receptor stimulation." in: The Journal of biological chemistry, Vol. 282, Issue 12, pp. 9117-26, (2007) (PubMed).
Synonyms and alternative names related to PPP2R1A
protein phosphatase 2 scaffold subunit Aalpha (PPP2R1A), protein phosphatase 2 scaffold subunit A alpha (Ppp2r1a), protein phosphatase 2 regulatory subunit A, alpha L homeolog (ppp2r1a.L), protein phosphatase 2 regulatory subunit A, alpha (ppp2r1a), protein phosphatase 2, regulatory subunit A, beta a (ppp2r1ba), serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (LOC583227), protein phosphatase 2, regulatory subunit A, alpha isoform (Ppp2r1a), protein phosphatase 2, regulatory subunit A, alpha (PPP2R1A), protein phosphatase 2, regulatory subunit A, alpha (Ppp2r1a), protein phosphatase 2 regulatory subunit A, alpha S homeolog (ppp2r1a.S), 6330556D22Rik, PP2A, PP2A-Aalpha, pp2a-aalpha, PP2AAALPHA, pp2aaalpha, ppp2r1a, ppp2r1a-a, ppp2r1a-b, PR65, PR65A, pr65a, wu:fa02h04, zgc:56296Protein level used designations for PPP2R1A
- PP2A subunit A isoform PR65-alpha
- PP2A subunit A isoform R1-alpha
- medium tumor antigen-associated 61 KDA protein
- protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform
- serine/threonine protein phosphatase 2A, 65 kDa regulatory subunit A, alpha isoform
- serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform
- alpha isoform of regulatory subunit A, protein phosphatase 2
- protein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform
- protein phosphatase 2 (formerly 2A), regulatory subunit A , alpha isoform
- protein phosphatase 2A 65 kDa regulatory subunit, alpha isoform
- protein phosphatase 2 (formerly 2A), regulatory subunit A, beta isoform
- medium tumor antigen-associated 61 kDa protein
- protein phosphatase 2, regulatory subunit A, alpha
- GLEAN_12508
- serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform-like
- protein phosphatase PP2A
- serine/threonine protein phosphatase A subunit type 2A
- protein phosphatase 2 regulatory subunit A, alpha S homeolog
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