PRPF8 Products
(PRP8 Pre-mRNA Processing Factor 8 (PRPF8))
Categories
Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis pigmentosa. [provided by RefSeq, Jul 2008].
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Featured PRPF8 Categories
PRPF8 Antibodies
High quality antibodies with extensive validation data.
Recommended PRPF8 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, IF
Validations
- (5)
Cat. No.
ABIN7261922
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, IF
Validations
- (5)
Cat. No.
ABIN6146268
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (5)
Cat. No.
ABIN7269737
Quantity
100 μL
Datasheet
Datasheet
Recommended PRPF8 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6233880
Quantity
96 tests
Datasheet
Datasheet
Recommended PRPF8 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1316402
Quantity
25 μg
Datasheet
Datasheet
Latest Publications for our PRPF8 products
: "Splicing Factor Prp8 Interacts With NES(AR) and Regulates Androgen Receptor in Prostate Cancer Cells." in: Molecular endocrinology (Baltimore, Md.), Vol. 29, Issue 12, pp. 1731-42, (2015) (PubMed).: "The core spliceosome as target and effector of non-canonical ATM signalling." in: Nature, Vol. 523, Issue 7558, pp. 53-8, (2015) (PubMed).
: "Cytoplasmic viral RNA-dependent RNA polymerase disrupts the intracellular splicing machinery by entering the nucleus and interfering with Prp8." in: PLoS pathogens, Vol. 10, Issue 6, pp. e1004199, (2014) (PubMed).
: "Metabolic profiling reveals PAFAH1B3 as a critical driver of breast cancer pathogenicity." in: Chemistry & biology, Vol. 21, Issue 7, pp. 831-40, (2014) (PubMed).
Synonyms and alternative names related to PRPF8
pre-mRNA processing factor 8 (Prpf8), pre-mRNA processing factor 8 (prpf8), pre-mRNA processing factor 8 S homeolog (prpf8.S), pre-mRNA processing factor 8 (PRPF8), AU019467, D11Bwg0410e, DBF3/PRP8, hprp8, HPRP8, id:ibd1257, ik:tdsubc_2a9, im:7141966, prp-8, prp8, PRP8, Prp8, prpc8, PRPC8, rp13, RP13, Sfprp8l, SNRNP220, tdsubc_2a9, wu:fb37c02, wu:fb73e06, xx:tdsubc_2a9, zgc:56504Protein level used designations for PRPF8
- PRP8 pre-mRNA processing factor 8 homolog
- pre-mRNA-processing-splicing factor 8
- 220 kDa U5 snRNP-specific protein
- PRP8 homolog
- U5 snRNP-specific protein (220 kD), ortholog of S. cerevisiae Prp8p
- apoptosis-regulated protein 1
- apoptosis-regulated protein 2
- p220
- precursor mRNA processing protein
- splicing factor Prp8
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