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PRRX1 Products

(Paired Related Homeobox 1 (PRRX1))

Categories

The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription co-activator, enhancing the DNA-binding activity of serum response factor, a protein required for the induction of genes by growth and differentiation factors. The protein regulates muscle creatine kinase, indicating a role in the establishment of diverse mesodermal muscle types. Alternative splicing yields two isoforms that differ in abundance and expression patterns. [provided by RefSeq, Jul 2008].

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Featured PRRX1 Categories

PRRX1 Antibodies

High quality antibodies with extensive validation data.

PRRX1 ELISA Kits

Reliable ELISA kits for a wide range of species.

PRRX1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PRRX1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (1)
  • (3)
Cat. No. ABIN1327183
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (3)
Cat. No. ABIN238608
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application IF, WB
Validations
  • (3)
Cat. No. ABIN519000
Quantity 50 μg
Datasheet Datasheet

Recommended PRRX1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method
Validations
Cat. No. ABIN1146874
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1146873
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1146872
Quantity 96 tests
Datasheet Datasheet

Recommended PRRX1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3086487
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3120819
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1316455
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our PRRX1 products

Song, Kim, Lim, Kim, Sung: "Expression and prognostic significance of epithelial-mesenchymal transition-related markers and phenotype in serous ovarian cancer." in: Pathology, research and practice, Vol. 214, Issue 10, pp. 1564-1571, (2018) (PubMed).

Zhu, Sun: "Loss of PRRX1 induces epithelial-mesenchymal transition and cancer stem cell-like properties in A549 cells." in: American journal of translational research, Vol. 9, Issue 4, pp. 1641-1650, (2017) (PubMed).

Yi, Kim, Chung, Ahn, Sim, Wi, Pyo, Song, Paik, Oh: "Clinicopathologic Correlations of E-cadherin and Prrx-1 Expression Loss in Hepatocellular Carcinoma." in: Journal of pathology and translational medicine, Vol. 50, Issue 5, pp. 327-36, (2016) (PubMed).

Hirata, Sugimachi, Takahashi, Ueda, Sakimura, Uchi, Kurashige, Takano, Nanbara, Komatsu, Saito, Shinden, Iguchi, Eguchi, Atsumi, Sakamoto, Doi, Hirakawa, Honda, Mimori: "Downregulation of PRRX1 Confers Cancer Stem Cell-Like Properties and Predicts Poor Prognosis in Hepatocellular Carcinoma." in: Annals of surgical oncology, (2014) (PubMed).

Guo, Fu, Wei, Lu, Feng, Zhang: "PRRX1 promotes epithelial-mesenchymal transition through the Wnt/?-catenin pathway in gastric cancer." in: Medical oncology (Northwood, London, England), Vol. 32, Issue 1, pp. 393, (2014) (PubMed).

Hardin, Guo, Shan, Montemayor-Garcia, Asioli, Yu, Harrison, Chen, Lloyd: "The roles of the epithelial-mesenchymal transition marker PRRX1 and miR-146b-5p in papillary thyroid carcinoma progression." in: The American journal of pathology, Vol. 184, Issue 8, pp. 2342-54, (2014) (PubMed).

Du, Cawthorn, Su, Doucette, Yao, Hemati, Kampert, McCoin, Broome, Rosen, Yang, MacDougald: "The transcription factor paired-related homeobox 1 (Prrx1) inhibits adipogenesis by activating transforming growth factor-? (TGF?) signaling." in: The Journal of biological chemistry, Vol. 288, Issue 5, pp. 3036-47, (2013) (PubMed).

Reichert, Takano, von Burstin, Kim, Lee, Ihida-Stansbury, Hahn, Heeg, Schneider, Rhim, Stanger, Rustgi: "The Prrx1 homeodomain transcription factor plays a central role in pancreatic regeneration and carcinogenesis." in: Genes & development, Vol. 27, Issue 3, pp. 288-300, (2013) (PubMed).

Jiang, Stefanovic: "Homeobox gene Prx1 is expressed in activated hepatic stellate cells and transactivates collagen alpha1(I) promoter." in: Experimental biology and medicine (Maywood, N.J.), Vol. 233, Issue 3, pp. 286-96, (2008) (PubMed).

Vieira, McHenry, Daack-Hirsch, Murray, Marazita: "Candidate gene/loci studies in cleft lip/palate and dental anomalies finds novel susceptibility genes for clefts." in: Genetics in medicine : official journal of the American College of Medical Genetics, Vol. 10, Issue 9, pp. 668-74, (2008) (PubMed).

Synonyms and alternative names related to PRRX1

paired related homeobox 1 (PRRX1), paired related homeobox 1 (Prrx1), paired related homeobox 1a (prrx1a), A230024N07Rik, AA755424, AGOTC, AI385634, AI843499, cb329, gMHox, homeobox, K-2, mHox, PHOX1, Pmx, PMX1, Pmx1, pmx1, prrx1, PRRX1, PRX-1, Prx-1, PRX1, Prx1, wu:fa09h05, wu:fb52c01, zgc:64055

Protein level used designations for PRRX1

  • homeobox protein PHOX1
  • paired mesoderm homeo box 1
  • paired mesoderm homeobox 1 isoform pmx-1b
  • paired mesoderm homeobox protein 1
  • paired-related homeobox protein 1
  • homeobox protein K-2
  • homeobox protein mHox
  • paired mesoderm homeobox 1
  • rHox
  • homeobox protein MHOX
  • paired-related homeotic gene product
  • paired related homeobox 1
  • prx1
  • LOW QUALITY PROTEIN: paired mesoderm homeobox protein 1
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