PAK1/2/3 Products
(P21-Activated Kinases 1/2/3 (PAK1/2/3))
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This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010].
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Featured PAK1/2/3 Categories
PAK1/2/3 Antibodies
High quality antibodies with extensive validation data.
Recommended PAK1/2/3 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
IHC, ELISA, WB
Validations
- (3)
Cat. No.
ABIN7180065
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
IHC, ELISA, WB
Validations
- (4)
Cat. No.
ABIN1847964
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
IHC, ELISA, IF
Validations
- (2)
Cat. No.
ABIN7138850
Quantity
100 μL
Datasheet
Datasheet
Recommended PAK1/2/3 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1380246
Quantity
2 x 96 tests
Datasheet
Datasheet
Latest Publications for our PAK1/2/3 products
: "P21-activated kinase 1 regulates resistance to BRAF inhibition in human cancer cells." in: Molecular carcinogenesis, Vol. 56, Issue 5, pp. 1515-1525, (2017) (PubMed).: "Very-low and low-density lipoproteins induce neutral lipid accumulation and impair migration in monocyte subsets." in: Scientific reports, Vol. 6, pp. 20038, (2016) (PubMed).
: "Spatially distinct binding of Cdc42 to PAK1 and N-WASP in breast carcinoma cells." in: Molecular and cellular biology, Vol. 25, Issue 5, pp. 1680-95, (2005) (PubMed).
: "VE-cadherin regulates endothelial actin activating Rac and increasing membrane association of Tiam." in: Molecular biology of the cell, Vol. 13, Issue 4, pp. 1175-89, (2002) (PubMed).
: "P21-activated kinase-1 phosphorylates and transactivates estrogen receptor-alpha and promotes hyperplasia in mammary epithelium." in: The EMBO journal, Vol. 21, Issue 20, pp. 5437-47, (2002) (PubMed).
: "Affecting long-term fear memory formation through optical control of Rac1 GTPase and PAK activity in lateral amygdala." in: Scientific reports, Vol. 7, Issue 1, pp. 13930 (PubMed).
Synonyms and alternative names related to PAK1/2/3
p21 protein (Cdc42/Rac)-activated kinase 1 S homeolog (pak1.S), p21 (RAC1) activated kinase 1 (PAK1), pak, pak-1, pakalpha, X-PAK1, XPak1Protein level used designations for PAK1/2/3
- p21 GTPase-associated kinase 1
- p21-activated kinase 1
- p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast)
- putative CDKN1A-activated kinase 1
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