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Annexin VIII Protein (AA 1-327)

This Recombinant Annexin VIII protein is expressed in Escherichia coli (E. coli).
Catalog No. ABIN1096026

Quick Overview for Annexin VIII Protein (AA 1-327) (ABIN1096026)

Target

See all Annexin VIII (ANXA8) Proteins
Annexin VIII (ANXA8) (Annexin A8 (ANXA8))

Protein Type

Recombinant

Origin

  • 8
  • 3
  • 1
  • 1
  • 1
  • 1
Human

Source

  • 6
  • 4
  • 3
  • 2
Escherichia coli (E. coli)

Purity

> 95 % as determined by reducing SDS-PAGE.
  • Protein Characteristics

    AA 1-327

    Purpose

    Recombinant Human Annexin A8/ANXA8

    Sequence

    MAWWKSWIEQ EGVTVKSSSH FNPDPDAETL YKAMKGIGTN EQAIIDVLTK RSNTQRQQIA KSFKAQFGKD LTETLKSELS GKFERLIVAL MYPPYRYEAK ELHDAMKGLG TKEGVIIEIL ASRTKNQLRE IMKAYEEDYG SSLEEDIQAD TSGYLERILV CLLQGSRDDV SSFVDPALAL QDAQDLYAAG EKIRGTDEMK FITILCTRSA THLLRVFEEY EKIANKSIED SIKSETHGSL EEAMLTVVKC TQNLHSYFAE RLYYAMKGAG TRDGTLIRNI VSRSEIDLNL IKCHFKKMYG KTLSSMIMED TSGDYKNALL SLVGSDP

    Characteristics

    Recombinant Human Annexin A8/ANXA8 is produced by our E. coli expression system. The target protein is expressed with sequence (Met1-Pro327) of Human ANXA8.

    Sterility

    0.2 μm filtered

    Endotoxin Level

    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

    Buffer

    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

    Handling Advice

    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

    Storage

    4 °C/-20 °C/-80 °C

    Storage Comment

    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    Expiry Date

    3 months
  • Target

    Annexin VIII (ANXA8) (Annexin A8 (ANXA8))

    Alternative Name

    annexin-a8

    Background

    Annexin A8 (ANXA8) belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Annexin A8 contains 4 annexin repeats separated by linking sequences of variable lengths. A pair of annexin repeats may form one binding site for calcium and phospholipid. ANXA8 is preferentially expressed in acute promyelocytic leukemia (APL) cells, which suggests its participation in hematopoietic cell differentiation. In addition, ANXA8 is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade.
    Alternative Names: Annexin A8, Annexin VIII, Annexin-8, Vascular Anticoagulant-Beta, VAC-Beta, ANXA8, ANX8

    Molecular Weight

    36.9 kDa

    UniProt

    P13928
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