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Annexin VIII Protein (His tag)

ANXA8 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7317192
  • Target See all Annexin VIII (ANXA8) Proteins
    Annexin VIII (ANXA8) (Annexin A8 (ANXA8))
    Protein Type
    Recombinant
    Origin
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 6
    • 4
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This Annexin VIII protein is labelled with His tag.
    Purpose
    Recombinant Human Annexin A8/ANXA8 Protein (His Tag)
    Sequence
    Met 1-Pro327
    Characteristics
    A DNA sequence encoding the human ANXA8 (AAH73755.1) (Met1-Pro327) was expressed with a polyhistidine tag at the N-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product ANXA8 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from sterile PBS, pH 7.4
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    Annexin VIII (ANXA8) (Annexin A8 (ANXA8))
    Alternative Name
    Annexin A8/ANXA8 (ANXA8 Products)
    Synonyms
    ANX8 Protein, ANXA8L1 Protein, ANXA8L2 Protein, AI466995 Protein, Anx8 Protein, anx8 Protein, MGC85309 Protein, ANXA8 Protein, annexin A8 Protein, annexin A8 S homeolog Protein, ANXA8 Protein, Anxa8 Protein, anxa8.S Protein, LOC694628 Protein, LOC100052045 Protein
    Background

    Background: DPEP2 (MBD-2) belongs to the membrane-bound dipeptidase family. There are three members of this family as membrane-bound dipeptidase-1 (MBD-1),membrane-bound dipeptidase-2 (MBD-2) and membrane-bound dipeptidase-3 (MBD-3).MBD-2 is expressed at highest levels in lung, heart, and testis and at some what lower levels in spleen.MBD-2 is membrane-bound through a glycosylphosphatidyl-inositol linkage and probably is a metalloprotease which hydrolyzes leukotriene D4 (LTD4) into leukotriene E4 (LTE4).It is generally recognized that rapid cleavage of LTD4 is important in inactivating the broncho-and vaso-constrictive effects of cysteinyl LTs in asthmatic and inflammatory processes.

    Synonym: Annexin A8, Annexin VIII, Annexin-8, Vascular Anticoagulant-Beta, VAC-Beta, ANXA8, ANX8

    Molecular Weight
    39.1 kDa
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