Annexin VIII Protein (His tag)
Quick Overview for Annexin VIII Protein (His tag) (ABIN7317192)
Target
See all Annexin VIII (ANXA8) ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This Annexin VIII protein is labelled with His tag.
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Purpose
- Recombinant Human Annexin A8/ANXA8 Protein (His Tag)
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Sequence
- Met 1-Pro327
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Characteristics
- A DNA sequence encoding the human ANXA8 (AAH73755.1) (Met1-Pro327) was expressed with a polyhistidine tag at the N-terminus.
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Sterility
- 0.2 μm filtered
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Biological Activity Comment
- Not validated for activity
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
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Lyophilized from sterile PBS, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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Expiry Date
- 12 months
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- Annexin VIII (ANXA8) (Annexin A8 (ANXA8))
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Alternative Name
- Annexin A8/ANXA8
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Background
- ANX8,ANXA8,Annexin A8,Annexin VIII,Annexin-8,VAC-Beta,Vascular Anticoagulant-Beta,DPEP2 (MBD-2) belongs to the membrane-bound dipeptidase family. There are three members of this family as membrane-bound dipeptidase-1 (MBD-1),membrane-bound dipeptidase-2 (MBD-2) and membrane-bound dipeptidase-3 (MBD-3).MBD-2 is expressed at highest levels in lung, heart, and testis and at some what lower levels in spleen.MBD-2 is membrane-bound through a glycosylphosphatidyl-inositol linkage and probably is a metalloprotease which hydrolyzes leukotriene D4 (LTD4) into leukotriene E4 (LTE4).It is generally recognized that rapid cleavage of LTD4 is important in inactivating the broncho-and vaso-constrictive effects of cysteinyl LTs in asthmatic and inflammatory processes.
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Molecular Weight
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Calculated MW: 39.1 kDa
Observed MW: 35 kDa
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Gene ID
- 653145
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UniProt
- P13928
Target
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