MOG Protein (AA 30-154) (His tag)

Catalog No. ABIN1097171

Recombinant MOG protein expressed in Escherichia coli (E. coli).

Quick Overview for MOG Protein (AA 30-154) (His tag) (ABIN1097171)

Target: MOG (Myelin Oligodendrocyte Glycoprotein (MOG))

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: Escherichia coli (E. coli)

Application: Functional Studies (Func)

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Protein Characteristics: AA 30-154

Purification tag / Conjugate: This MOG protein is labelled with His tag.

Purpose: Recombinant Human Myelin Oligodendrocyte Glycoprotein/MOG

Sequence: MGQFRVIGPR HPIRALVGDE VELPCRISPG KNATGMEVGW YRPPFSRVVH LYRNGKDQDG DQAPEYRGRT ELLKDAIGEG KVTLRIRNVR FSDEGGFTCF FRDHSYQEEA AMELKVEDPF YWVSPGHHHH HH

Characteristics: Recombinant Human Myelin Oligodendrocyte Glycoprotein is produced by our E.coli expression system and the target gene encoding Gly30-Gly154 is expressed with a 6His tag at the C-terminus.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Comment:

Biological activity: Tested for capability to induce EAE in rodents and monkeys

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 um filtered solution of 20 mM HAc-NaAc, 150 mM NaCl, pH 4.5.

Storage: 4 °C,-20 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 3 weeks

Target Details

Target: MOG (Myelin Oligodendrocyte Glycoprotein (MOG))

Alternative Name: mog-protein

Background: Alternative Names: Myelin-Oligodendrocyte Glycoprotein, MOGMyelin Oligodendrocyte Glycoprotein (MOG) is a transmembrane protein, which is expressed exclusively in the CNS. MOG contains a single Ig-domain exposed to the extracellular space that allows autoantibodies easy access. MOG protein has been identified as a crucial autoantigen for multiple sclerosis in humans. MOG is capable to produce a demyelinating multiple sclerosis-like diseases in experimental animals, namely experimental autoimmune encephalomyelitis (EAE), in rodents and monkeys.
Alternative Names: Myelin-Oligodendrocyte Glycoprotein, MOG

Molecular Weight: 15.2 kDa

UniProt: Q16653