MOG Protein (His tag)
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- Target See all MOG Proteins
- MOG (Myelin Oligodendrocyte Glycoprotein (MOG))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This MOG protein is labelled with His tag.
- Purpose
- Active Recombinant Human Myelin-oligodendrocyte glycoprotein/MOG Protein
- Sequence
- GQFRVIGPRH PIRALVGDEV ELPCRISPGK NATGMEVGWY RPPFSRVVHL YRNGKDQDGD QAPEYRGRTE LLKDAIGEGK VTLRIRNVRF SDEGGFTCFF RDHSYQEEAA MELKVEDPFY WVSPG
- Specificity
- Gly30-Gly154
- Purity
- > 95 % by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- <0.1EU/μg
- Biological Activity Comment
- Measured by its binding ability in a functional ELISA. Immobilized Human MOG at 1 μg/mL (100 μL/well) can bind Myelin oligodendrocyte glycoprotein Rabbit mAb with a linear range of 0.98-2.5 ng/mL
- Top Product
- Discover our top product MOG Protein
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Myelin Oligodendrocyte Glycoprotein (MOG) (AA 1-295) protein (GST tag)
MOG Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Myelin Oligodendrocyte Glycoprotein (MOG) (AA 30-154) protein (His tag)Crystallography grade MOG Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Myelin Oligodendrocyte Glycoprotein (MOG) (AA 29-156) protein (His tag)Crystallography grade MOG Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Myelin Oligodendrocyte Glycoprotein (MOG) (AA 30-247) protein (rho-1D4 tag)Crystallography grade MOG Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Myelin Oligodendrocyte Glycoprotein (MOG) (AA 29-246) protein (rho-1D4 tag)Crystallography grade MOG Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
- Buffer
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store the lyophilized protein at -20°C to -80°C for long term.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
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- Target
- MOG (Myelin Oligodendrocyte Glycoprotein (MOG))
- Alternative Name
- Myelin-oligodendrocyte glycoprotein/MOG (MOG Products)
- Synonyms
- MOGIG2 Protein, NRCLP7 Protein, B230317G11Rik Protein, MOG Protein, myelin oligodendrocyte glycoprotein Protein, MOG Protein, Mog Protein
- Background
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Description: Myelin oligodendrocyte glycoprotein (MOG) is a transmembrane protein belonging to the immunoglobulin superfamily and contains an Ig-like domain followed by two potential membrane-spanning regions. MOG is expressed only in the CNS with very low content (approximately 0.1 % total proteins) in the oligodendrogliocyte membrane. Three possible functions for MOG were suggested: (a) a cellular adhesive molecule, (b) a regulator of oligodendrocyte microtubule stability, and (c) a mediator of interactions between myelin and the immune system, in particular, the complement cascade. A direct interaction might exist between the membrane-associated regions of MOG and the myelin-specific glycolipid galactocerebroside (Gal-C), and such an interaction may have important consequences regarding the membrane topology and function of both molecules. It is considered that MOG is an autoantigen capable to produce demyelinating multiple sclerosis-like diseases in experimental animals.
Name: BTN6, BTNL11, MOGIG2, NRCLP7,MOG,BTNL11,MOGIG2,NRCLP7
- Gene ID
- 4340
- UniProt
- Q16653
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