Neurotrophin 3 Protein (NTF3) (AA 139-257)
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- Target See all Neurotrophin 3 (NTF3) Proteins
- Neurotrophin 3 (NTF3)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 139-257
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purpose
- Recombinant Human Neurotrophin-3/NT3
- Sequence
- YAEHKSHRGE YSVCDSESLW VTDKSSAIDI RGHQVTVLGE IKTGNSPVKQ YFYETRCKEA RPVKNGCRGI DDKHWNSQCK TSQTYVRALT SENNKLVGWR WIRIDTSCVC ALSRKIGRT
- Characteristics
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Recombinant Human Neurotrophin-3/NT3
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product NTF3 Protein
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Neurotrophin 3 (NTF3) (Active) protein
NTF3 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant SDS, Func Active
Neurotrophin 3 (NTF3) (AA 1-257) protein (GST tag)NTF3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Neurotrophin 3 (NTF3) (AA 19-128) protein (GST tag)NTF3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Neurotrophin 3 (NTF3) (AA 139-257) protein (His tag)Crystallography grade NTF3 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Neurotrophin 3 (NTF3) (AA 140-258) protein (His tag)Crystallography grade NTF3 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 250 mM NaCl, pH 7.2.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- 4 °C/-20 °C/-80 °C
- Storage Comment
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- Neurotrophin 3 (NTF3)
- Alternative Name
- Neurotrophin-3/NT3 (NTF3 Products)
- Synonyms
- HDNF Protein, NGF-2 Protein, NGF2 Protein, NT3 Protein, NT-3 Protein, wu:fl98d04 Protein, hdnf Protein, ngf-2 Protein, ngf2 Protein, nt-3 Protein, nt3 Protein, NTF3 Protein, AI316846 Protein, AI835689 Protein, Nt3 Protein, Ntf-3 Protein, neurotrophin 3 Protein, neurotrophin 3 S homeolog Protein, neurotrophin 3 L homeolog Protein, NTF3 Protein, ntf3 Protein, ntf3.S Protein, Ntf3 Protein, ntf3.L Protein
- Background
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Recombinant Human Neurotrophin-3/NT3 produced in E. coli is a single non-glycosylated polypeptide chain containing 119 AAs with a molecular mass of 13.6 kDa.
Neurotrophin-3 (NT-3) is a member of the NGF family of neurotrophic factors and is structurally related to β-NGF, BDNF and NT-4. The NT3 cDNA encodes a 257 AA residue precursor protein with a signal peptide and a proprotein that are cleaved to yield the 119 AA residue mature NT3.The AA sequences of mature human, murine and rat NT-3 are identical. NT-3 selectively promotes the differentiation and survival of specific neuronal subpopulations in both the central as well as the peripheral nervous systems. - Molecular Weight
- 13.6 kDa
- UniProt
- P20783
- Pathways
- RTK Signaling, Neurotrophin Signaling Pathway
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