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ST6GAL1 Protein (AA 27-406) (His tag)

ST6GAL1 Origin: Human Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN1097583
  • Target See all ST6GAL1 Proteins
    ST6GAL1 (ST6 beta-Galactosamide alpha-2,6-Sialyltranferase 1 (ST6GAL1))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 27-406
    Origin
    • 8
    • 3
    • 2
    Human
    Source
    • 4
    • 4
    • 2
    • 2
    • 1
    Human Cells
    Purification tag / Conjugate
    This ST6GAL1 protein is labelled with His tag.
    Purpose
    Recombinant Human β-Galactoside α-2,6-Sialyltransferase 1/ST6GAL1 (C-6His)
    Sequence
    KEKKKGSYYD SFKLQTKEFQ VLKSLGKLAM GSDSQSVSSS STQDPHRGRQ TLGSLRGLAK AKPEASFQVW NKDSSSKNLI PRLQKIWKNY LSMNKYKVSY KGPGPGIKFS AEALRCHLRD HVNVSMVEVT DFPFNTSEWE GYLPKESIRT KAGPWGRCAV VSSAGSLKSS QLGREIDDHD AVLRFNGAPT ANFQQDVGTK TTIRLMNSQL VTTEKRFLKD SLYNEGILIV WDPSVYHSDI PKWYQNPDYN FFNNYKTYRK LHPNQPFYIL KPQMPWELWD ILQEISPEEI QPNPPSSGML GIIIMMTLCD QVDIYEFLPS KRKTDVCYYY QKFFDSACTM GAYHPLLYEK NLVKHLNQGT DEDIYLLGKA TLPGFRTIHC VDHHHHHH
    Characteristics
    Recombinant Human beta-Galactoside alpha-2,6-Sialyltransferase 1/ST6GAL1 produced by transfected human cells is a secreted protein with sequence (Lys27-Cys406) of Human ST6GAL1 fused with a polyhistidine tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Sterility
    0.2 μm filtered
    Endotoxin Level
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product ST6GAL1 Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Reconstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 8.0.
    Handling Advice
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Storage
    -80 °C
    Storage Comment
    Store at < -20°C, stable for 6 months after receipt.
    Please minimize freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    ST6GAL1 (ST6 beta-Galactosamide alpha-2,6-Sialyltranferase 1 (ST6GAL1))
    Alternative Name
    st6gal1 (ST6GAL1 Products)
    Synonyms
    SIAT1 Protein, ST6GalI Protein, ST6N Protein, Siat1 Protein, siat1 Protein, zgc:136454 Protein, ST6GAL1 Protein, AW742324 Protein, St6Gal-I Protein, St6gal Protein, St6galI Protein, ST6 beta-galactoside alpha-2,6-sialyltransferase 1 Protein, ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 Protein, beta galactoside alpha 2,6 sialyltransferase 1 Protein, ST6GAL1 Protein, St6gal1 Protein, st6gal1 Protein
    Sub Type
    Fusionprotein
    Background
    The ST6GAL1 gene encodes beta-Galactosamide alpha-2,6-Sialyltransferase 1. It is a type II membrane protein and is localized to the trans-Golgi network. It catalyzes 2,6-sialylation of Galbeta1,4-GlcNAc structures on N-glycans. ST6GAL1 is highly expressed in the liver and other tissues. ST6GAL1 deficiency causes abnormalities in B-cell immunoreactivity. The expression and activity of ST6GAL1 are associated with tumor metastasis in breast and colon cancers. The majority of ST6GAL1 in the liver is cleaved and secreted into the serum and may be used as a biomarker for hepatitis diseases.
    Alternative Names: Beta-Galactoside Alpha-2,6-Sialyltransferase 1, Alpha 2,6-ST 1, B-Cell Antigen CD75, CMP-N-Acetylneuraminate-Beta-Galactosamide-Alpha-2,6-Sialyltransferase 1, ST6Gal I, ST6GalI, Sialyltransferase 1, ST6GAL1, SIAT1
    Molecular Weight
    44.6 kDa
    UniProt
    P15907
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