ST6GAL1 Protein (AA 27-406) (His tag)
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- Target See all ST6GAL1 Proteins
- ST6GAL1 (ST6 beta-Galactosamide alpha-2,6-Sialyltranferase 1 (ST6GAL1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 27-406
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This ST6GAL1 protein is labelled with His tag.
- Purpose
- Recombinant Human β-Galactoside α-2,6-Sialyltransferase 1/ST6GAL1 (C-6His)
- Sequence
- KEKKKGSYYD SFKLQTKEFQ VLKSLGKLAM GSDSQSVSSS STQDPHRGRQ TLGSLRGLAK AKPEASFQVW NKDSSSKNLI PRLQKIWKNY LSMNKYKVSY KGPGPGIKFS AEALRCHLRD HVNVSMVEVT DFPFNTSEWE GYLPKESIRT KAGPWGRCAV VSSAGSLKSS QLGREIDDHD AVLRFNGAPT ANFQQDVGTK TTIRLMNSQL VTTEKRFLKD SLYNEGILIV WDPSVYHSDI PKWYQNPDYN FFNNYKTYRK LHPNQPFYIL KPQMPWELWD ILQEISPEEI QPNPPSSGML GIIIMMTLCD QVDIYEFLPS KRKTDVCYYY QKFFDSACTM GAYHPLLYEK NLVKHLNQGT DEDIYLLGKA TLPGFRTIHC VDHHHHHH
- Characteristics
- Recombinant Human beta-Galactoside alpha-2,6-Sialyltransferase 1/ST6GAL1 produced by transfected human cells is a secreted protein with sequence (Lys27-Cys406) of Human ST6GAL1 fused with a polyhistidine tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product ST6GAL1 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 8.0.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- -80 °C
- Storage Comment
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - Expiry Date
- 6 months
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- Target
- ST6GAL1 (ST6 beta-Galactosamide alpha-2,6-Sialyltranferase 1 (ST6GAL1))
- Alternative Name
- st6gal1 (ST6GAL1 Products)
- Synonyms
- SIAT1 Protein, ST6GalI Protein, ST6N Protein, Siat1 Protein, siat1 Protein, zgc:136454 Protein, ST6GAL1 Protein, AW742324 Protein, St6Gal-I Protein, St6gal Protein, St6galI Protein, ST6 beta-galactoside alpha-2,6-sialyltransferase 1 Protein, ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 Protein, beta galactoside alpha 2,6 sialyltransferase 1 Protein, ST6GAL1 Protein, St6gal1 Protein, st6gal1 Protein
- Sub Type
- Fusionprotein
- Background
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The ST6GAL1 gene encodes beta-Galactosamide alpha-2,6-Sialyltransferase 1. It is a type II membrane protein and is localized to the trans-Golgi network. It catalyzes 2,6-sialylation of Galbeta1,4-GlcNAc structures on N-glycans. ST6GAL1 is highly expressed in the liver and other tissues. ST6GAL1 deficiency causes abnormalities in B-cell immunoreactivity. The expression and activity of ST6GAL1 are associated with tumor metastasis in breast and colon cancers. The majority of ST6GAL1 in the liver is cleaved and secreted into the serum and may be used as a biomarker for hepatitis diseases.
Alternative Names: Beta-Galactoside Alpha-2,6-Sialyltransferase 1, Alpha 2,6-ST 1, B-Cell Antigen CD75, CMP-N-Acetylneuraminate-Beta-Galactosamide-Alpha-2,6-Sialyltransferase 1, ST6Gal I, ST6GalI, Sialyltransferase 1, ST6GAL1, SIAT1 - Molecular Weight
- 44.6 kDa
- UniProt
- P15907
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