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ST6GAL1 Protein (His tag)

ST6GAL1 Origin: Human Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7319313
  • Target See all ST6GAL1 Proteins
    ST6GAL1 (ST6 beta-Galactosamide alpha-2,6-Sialyltranferase 1 (ST6GAL1))
    Protein Type
    Recombinant
    Origin
    • 8
    • 3
    • 2
    Human
    Source
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    Human Cells
    Purification tag / Conjugate
    This ST6GAL1 protein is labelled with His tag.
    Purpose
    Recombinant Human ST6GAL1 Protein (His Tag)
    Sequence
    Lys27-Cys406
    Characteristics
    Recombinant Human beta-Galactoside alpha-2,6-Sialyltransferase 1 is produced by our Mammalian expression system and the target gene encoding Lys27-Cys406 is expressed with a 6His tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product ST6GAL1 Protein
  • Restrictions
    For Research Use only
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 8.0.
    Storage
    -20 °C
    Storage Comment
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target
    ST6GAL1 (ST6 beta-Galactosamide alpha-2,6-Sialyltranferase 1 (ST6GAL1))
    Alternative Name
    ST6GAL1 (ST6GAL1 Products)
    Synonyms
    SIAT1 Protein, ST6GalI Protein, ST6N Protein, Siat1 Protein, siat1 Protein, zgc:136454 Protein, ST6GAL1 Protein, AW742324 Protein, St6Gal-I Protein, St6gal Protein, St6galI Protein, ST6 beta-galactoside alpha-2,6-sialyltransferase 1 Protein, ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 Protein, beta galactoside alpha 2,6 sialyltransferase 1 Protein, ST6GAL1 Protein, St6gal1 Protein, st6gal1 Protein
    Background

    Background: The ST6GAL1 gene encodes β-Galactosamide α-2,6-Sialyltransferase 1. It is a type II membrane protein and is localized to the trans-Golgi network. It catalyzes 2,6-sialylation of Galβ1,4-GlcNAc structures on N-glycans. ST6GAL1 is highly expressed in the liver and other tissues. ST6GAL1 deficiency causes abnormalities in B-cell immunoreactivity. The expression and activity of ST6GAL1 are associated with tumor metastasis in breast and colon cancers. The majority of ST6GAL1 in the liver is cleaved and secreted into the serum and may be used as a biomarker for hepatitis diseases.

    Synonym: Beta-Galactoside Alpha-2,6-Sialyltransferase 1, Alpha 2,6-ST 1, B-Cell Antigen CD75, CMP-N-Acetylneuraminate-Beta-Galactosamide-Alpha-2,6-Sialyltransferase 1, ST6Gal I, ST6GalI, Sialyltransferase 1, ST6GAL1, SIAT1

    Molecular Weight
    44.6 kDa
    UniProt
    P15907
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