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2B4 Protein (AA 19-224) (His tag)

This Recombinant 2B4 protein is produced in Escherichia coli (E. coli).
Catalog No. ABIN7676564
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Quick Overview for 2B4 Protein (AA 19-224) (His tag) (ABIN7676564)

Target

See all 2B4 (CD244) Proteins
2B4 (CD244) (Natural Killer Cell Receptor 2B4 (CD244))

Protein Type

Recombinant

Origin

  • 22
  • 7
  • 3
Human

Source

  • 14
  • 6
  • 5
  • 2
  • 2
  • 1
  • 1
  • 1
Escherichia coli (E. coli)

Application

SDS-PAGE (SDS)

Purity

> 85 %
  • Protein Characteristics

    AA 19-224

    Purification tag / Conjugate

    This 2B4 protein is labelled with His tag.

    Sequence

    MGSSHHHHHH SSGLVPRGSH MGSHGKGCQG SADHVVSISG VPLQLQPNSI QTKVDSIAWK KLLPSQNGFH HILKWENGSL PSNTSNDRFS FIVKNLSLLI KAAQQQDSGL YCLEVTSISG KVQTATFQVF VFDKVEKPRL QGQGKILDRG RCQVALSCLV SRDGNVSYAW YRGSKLIQTA GNLTYLDEEV DINGTHTYTC NVSNPVSWES HTLNLTQDCQ NAHQEFRFWP

    Purification

    > 85% by SDS-PAGE
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  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.5 mg/mL

    Buffer

    20 mM Tris-HCl buffer ( pH 8.0) containing 0.4M urea

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
  • Target

    2B4 (CD244) (Natural Killer Cell Receptor 2B4 (CD244))

    Alternative Name

    2B4/CD244

    Background

    CD244 (Natural Killer Cell Receptor 2B4), also known as Cluster of Differentiation 244, contains 2 Ig-like (immunoglobulin-like) domains. A role for the subtypes of CD2 Ig superfamily receptors has been recently demonstrated in eosinophilic inflammation in experimental asthma and atopic asthmatics. Functions of CD244 Molecules are in eosinophil adhesion and chemotaxis, and correlated the results to the pathophysiology of allergic rhinitis (AR). The cluster of differentiation (cluster of designation) (often abbreviated as CD) is a protocol used for the identification and investigation of cell surface molecules present on white blood cells initially but found in almost any kind of cell of the body, providing targets for immunophenotyping of cells. Recombinant human CD244 protein, fused to His-tag at N-terminus, was expressed in E. coli.

    Molecular Weight

    25.5 kDa (230aa)

    NCBI Accession

    NP_057466
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