2B4 Protein (AA 22-221) (Fc Tag)
Quick Overview for 2B4 Protein (AA 22-221) (Fc Tag) (ABIN2180732)
Target
See all 2B4 (CD244) ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Protein Characteristics
- AA 22-221
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Purification tag / Conjugate
- This 2B4 protein is labelled with Fc Tag.
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Sequence
- AA 22-221
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Characteristics
- This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 48.9 kDa. As a result of glycosylation, the protein migrates as 65-80 kDa under reducing (R) condition, and 130-160 kDa under non-reducing (NR) condition (SDS-PAGE).
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Sterility
- 0.22 μm filtered
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Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
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Natural Killer Cell Receptor 2B4 (CD244) (AA 22-221) (Active) protein (His tag)
CD244 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 90 % as determined by HPLC Active
Natural Killer Cell Receptor 2B4 (CD244) (AA 22-221) (Active) protein (Biotin,His-Avi Tag)CD244 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Natural Killer Cell Receptor 2B4 (CD244) (AA 22-216) protein (His tag,mFc Tag)CD244 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
Natural Killer Cell Receptor 2B4 (CD244) (AA 22-216) protein (Fc Tag)CD244 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
Natural Killer Cell Receptor 2B4 (CD244) (AA 22-221) protein (His tag,AVI tag,Biotin)CD244 Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE.
Natural Killer Cell Receptor 2B4 (CD244) protein (His tag)CD244 Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE
Natural Killer Cell Receptor 2B4 (CD244) (AA 20-225) protein (Fc Tag)CD244 Origin: Mouse Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
Natural Killer Cell Receptor 2B4 (CD244) (AA 1-365) protein (GST tag)CD244 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Natural Killer Cell Receptor 2B4 (CD244) (AA 19-224) protein (His tag)CD244 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 85 % SDS
Natural Killer Cell Receptor 2B4 (CD244) (AA 19-224) (Active) protein (hIgG-His-tag)CD244 Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 90 % SDS, AcA Active
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH 7.5
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Handling Advice
- Please avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
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- 2B4 (CD244) (Natural Killer Cell Receptor 2B4 (CD244))
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Alternative Name
- 2B4
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Background
- Natural killer cell receptor 2B4 is also known as NK cell type I receptor protein 2B4 (NKR2B4 or h2B4), SLAM family member 4 (SLAMF4), Signaling lymphocytic activation molecule 4, CD antigen CD244. NKR2B4 / CD244 contains two Ig-like (immunoglobulin-like) domains. CD244 is expressed in spleen, PBL, followed by lung, liver, testis and small intestine. CD244 interacts with CD48. Following phosphorylation, CD244 is able to recruit PTPN11/SHP-2 and SH2D1A/SAP. SLAMF4 modulate other receptor-ligand interactions to enhance leukocyte activation. CD244/2B4 is the only heterophilic receptor of SLAM family.
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Molecular Weight
- 48.9 kDa
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NCBI Accession
- NP_057466
Target
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