CRLF2 Protein (His tag)
Quick Overview for CRLF2 Protein (His tag) (ABIN1098797)
Target
See all CRLF2 ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This CRLF2 protein is labelled with His tag.
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Comment
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Synonyms: Cytokine receptor-like factor 2 isoform 1 precursor, CRL2, CRLF2Y, TSLPR
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/ml (determined by Bradford assay)
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Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M UREA, 10% glycerol
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Storage
- 4 °C
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Storage Comment
- Avoid repeated freezing and thawing cycles.
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- CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))
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Alternative Name
- CRLF2
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Background
- CRLF2 is a receptor for thymic stromal lymphopoietin (TSLP). Together with the interleukin 7 receptor (IL7R), the protein and TSLP activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system. Two transcript variants encoding different isoforms have been found for this gene. Recombinant human CRLF2 protein, fused to His-tag at N-terminus, was expressed in E.coli.
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Molecular Weight
- 26.6 kDa (232aa)
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NCBI Accession
- NP_071431
Target
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