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Mesothelin Protein (MSLN) (AA 1-621) (GST tag)

Recombinant Mesothelin protein expressed in Wheat germ and has been mentioned in 1 publication.
Catalog No. ABIN1311459
$488.72
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Quick Overview for Mesothelin Protein (MSLN) (AA 1-621) (GST tag) (ABIN1311459)

Target

See all Mesothelin (MSLN) Proteins
Mesothelin (MSLN)

Protein Type

Recombinant

Origin

  • 49
  • 11
  • 5
  • 2
Human

Source

  • 46
  • 8
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
Wheat germ

Application

Western Blotting (WB), ELISA, Affinity Purification (AP), Antibody Array (AA)
  • Protein Characteristics

    AA 1-621

    Purification tag / Conjugate

    This Mesothelin protein is labelled with GST tag.

    Purpose

    MSLN (Human) Recombinant Protein (P01)

    Sequence

    MALPTARPLL GSCGTPALGS LLFLLFSLGW VQPSRTLAGE TGQAAPLDGV LANPPNISSL SPRQLLGFPC AEVSGLSTER VRELAVALAQ KNVKLSTEQL RCLAHRLSEP PEDLDALPLD LLLFLNPDAF SGPQACTRFF SRITKANVDL LPRGAPERQR LLPAALACWG VRGSLLSEAD VRALGGLACD LPGRFVAESA EVLLPRLVSC PGPLDQDQQE AARAALQGGG PPYGPPSTWS VSTMDALRGL LPVLGQPIIR SIPQGIVAAW RQRSSRDPSW RQPERTILRP RFRREVEKTA CPSGKKAREI DESLIFYKKW ELEACVDAAL LATQMDRVNA IPFTYEQLDV LKHKLDELYP QGYPESVIQH LGYLFLKMSP EDIRKWNVTS LETLKALLEV NKGHEMSPQV ATLIDRFVKG RGQLDKDTLD TLTAFYPGYL CSLSPEELSS VPPSSIWAVR PQDLDTCDPR QLDVLYPKAR LAFQNMNGSE YFVKIQSFLG GAPTEDLKAL SQQNVSMDLA TFMKLRTDAV LPLTVAEVQK LLGPHVEGLK AEERHRPVRD WILRQRQDDL DTLGLGLQGG IPNGYLVLDL SVQEALSGTP CLLGPGPVLT VLALLLASTL A

    Characteristics

    Human MSLN full-length ORF ( AAH03512.1, 1 a.a. - 621 a.a.) recombinant protein with GST-tag at N-terminal.

    Purification

    in vitro wheat germ expression system
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  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Comment

    Preparation method: in vitro, wheat germ expression system
    Product Quality tested by: 12.5% SDS-PAGE Stained with Coomassie Blue.

    Restrictions

    For Research Use only
  • Buffer

    50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.

    Handling Advice

    Aliquot to avoid repeated freezing and thawing.

    Storage

    -80 °C

    Storage Comment

    Best use within three months from the date of receipt of this protein.
  • Chang, Chen, Chen, Chiang, Chen, Mao, Lin, Lin Chiang, Cheng: "Mesothelin enhances invasion of ovarian cancer by inducing MMP-7 through MAPK/ERK and JNK pathways." in: The Biochemical journal, Vol. 442, Issue 2, pp. 293-302, (2012) (PubMed).

  • Target

    Mesothelin (MSLN)

    Alternative Name

    MSLN

    Background

    Full Gene Name: mesothelin
    Synonyms: CAK1,MPF,SMR

    Gene ID

    10232

    Pathways

    EGFR Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process
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