Mesothelin Protein (MSLN) (AA 1-621) (GST tag)
Quick Overview for Mesothelin Protein (MSLN) (AA 1-621) (GST tag) (ABIN1311459)
Target
See all Mesothelin (MSLN) ProteinsProtein Type
Origin
Source
Application
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Protein Characteristics
- AA 1-621
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Purification tag / Conjugate
- This Mesothelin protein is labelled with GST tag.
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Purpose
- MSLN (Human) Recombinant Protein (P01)
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Sequence
- MALPTARPLL GSCGTPALGS LLFLLFSLGW VQPSRTLAGE TGQAAPLDGV LANPPNISSL SPRQLLGFPC AEVSGLSTER VRELAVALAQ KNVKLSTEQL RCLAHRLSEP PEDLDALPLD LLLFLNPDAF SGPQACTRFF SRITKANVDL LPRGAPERQR LLPAALACWG VRGSLLSEAD VRALGGLACD LPGRFVAESA EVLLPRLVSC PGPLDQDQQE AARAALQGGG PPYGPPSTWS VSTMDALRGL LPVLGQPIIR SIPQGIVAAW RQRSSRDPSW RQPERTILRP RFRREVEKTA CPSGKKAREI DESLIFYKKW ELEACVDAAL LATQMDRVNA IPFTYEQLDV LKHKLDELYP QGYPESVIQH LGYLFLKMSP EDIRKWNVTS LETLKALLEV NKGHEMSPQV ATLIDRFVKG RGQLDKDTLD TLTAFYPGYL CSLSPEELSS VPPSSIWAVR PQDLDTCDPR QLDVLYPKAR LAFQNMNGSE YFVKIQSFLG GAPTEDLKAL SQQNVSMDLA TFMKLRTDAV LPLTVAEVQK LLGPHVEGLK AEERHRPVRD WILRQRQDDL DTLGLGLQGG IPNGYLVLDL SVQEALSGTP CLLGPGPVLT VLALLLASTL A
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Characteristics
- Human MSLN full-length ORF ( AAH03512.1, 1 a.a. - 621 a.a.) recombinant protein with GST-tag at N-terminal.
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Purification
- in vitro wheat germ expression system
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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Preparation method: in vitro, wheat germ expression system
Product Quality tested by: 12.5% SDS-PAGE Stained with Coomassie Blue. -
Restrictions
- For Research Use only
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Buffer
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.
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Handling Advice
- Aliquot to avoid repeated freezing and thawing.
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Storage
- -80 °C
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Storage Comment
- Best use within three months from the date of receipt of this protein.
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: "Mesothelin enhances invasion of ovarian cancer by inducing MMP-7 through MAPK/ERK and JNK pathways." in: The Biochemical journal, Vol. 442, Issue 2, pp. 293-302, (2012) (PubMed).
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: "Mesothelin enhances invasion of ovarian cancer by inducing MMP-7 through MAPK/ERK and JNK pathways." in: The Biochemical journal, Vol. 442, Issue 2, pp. 293-302, (2012) (PubMed).
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- Mesothelin (MSLN)
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Alternative Name
- MSLN
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Background
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Full Gene Name: mesothelin
Synonyms: CAK1,MPF,SMR -
Gene ID
- 10232
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Pathways
- EGFR Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process
Target
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