FGF21 Protein (AA 1-209) (Fc Tag)
Quick Overview for FGF21 Protein (AA 1-209) (Fc Tag) (ABIN1344033)
Target
See all FGF21 ProteinsProtein Type
Biological Activity
Origin
Source
Application
Purity
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Protein Characteristics
- AA 1-209
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Purification tag / Conjugate
- This FGF21 protein is labelled with Fc Tag.
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Purpose
- FGF-21 (human):Fc (human) (rec.)
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Cross-Reactivity
- Human
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Characteristics
- Human FGF-21 (aa 1-209) is fused at the C-terminus to the Fc portion of human IgG1.
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Sterility
- Sterile filtered
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Endotoxin Level
- <0.1EU/μg purified protein (LAL test).
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Biological Activity Comment
- Activates ERK and FRS2alpha phosphorylation in bKlotho expressing cells.
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Fibroblast Growth Factor 21 (FGF21) (AA 29-209) (Active) protein (mFc-Avi Tag)
FGF21 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Fibroblast Growth Factor 21 (FGF21) (AA 29-209) (Active) protein (mFc-Avi Tag,Biotin)FGF21 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Fibroblast Growth Factor 21 (FGF21) (AA 29-209) (Active) protein (His tag)FGF21 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE Active
Fibroblast Growth Factor 21 (FGF21) (AA 29-210) (Active) protein (His tag)FGF21 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Fibroblast Growth Factor 21 (FGF21) (AA 29-209) (Active) protein (His tag)FGF21 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Fibroblast Growth Factor 21 (FGF21) (AA 30-209) protein (GST tag)FGF21 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Fibroblast Growth Factor 21 (FGF21) (Active) proteinFGF21 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Fibroblast Growth Factor 21 (FGF21) protein (His tag)FGF21 Origin: Mouse Host: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE.
Fibroblast Growth Factor 21 (FGF21) protein (His tag)FGF21 Origin: Cynomolgus Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Fibroblast Growth Factor 21 (FGF21) (AA 29-209) protein (Fc Tag)FGF21 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ScA, IA, ADA, AM
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- 0.2μm-filtered solution in PBS.
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Handling Advice
- After opening, prepare aliquots and store at -20 °C. Avoid freeze/thaw cycles. For maximum product recovery after thawing, centrifuge the vial before opening the cap.
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Storage
- 4 °C,-20 °C
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Storage Comment
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Short Term Storage: +4°C
Long Term Storage: -20°C
Use & Stability: Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
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Expiry Date
- 6 months
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- FGF21 (Fibroblast Growth Factor 21 (FGF21))
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Alternative Name
- FGF-21
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Background
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Fibroblast Growth Factor 21
FGF-21 (Fibroblast growth factor 21) stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity requires the presence of betaKlotho.
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Molecular Weight
- ~50kDa (SDS-PAGE)
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UniProt
- Q9NSA1
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Pathways
- RTK Signaling
Target
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