BCMA Protein (AA 1-46) (Fc Tag)
Quick Overview for BCMA Protein (AA 1-46) (Fc Tag) (ABIN1344200)
Target
See all BCMA (TNFRSF17) ProteinsProtein Type
Biological Activity
Origin
Source
Application
Purity
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Protein Characteristics
- AA 1-46
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Purification tag / Conjugate
- This BCMA protein is labelled with Fc Tag.
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Purpose
- BCMA (mouse):Fc (human) (rec.)
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Specificity
- Binds mouse and human BAFF and APRIL.
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Cross-Reactivity
- Human, Mouse
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Characteristics
- The extracellular domain of mouse BCMA (aa 1-46) is fused at the C-terminus to the Fc portion of human IgG1.
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Endotoxin Level
- <0.01EU/μg purified protein (LAL test).
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Biological Activity Comment
- Blocks the binding of mouse BAFF and human APRIL to their receptors BCMA and TACI.
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Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17) (AA 1-54) protein (His-Avi Tag)
TNFRSF17 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17) (AA 1-54) protein (mFc Tag)TNFRSF17 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ScA, IA, ADA, AM
Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17) (AA 1-53) (Active) protein (hFc Tag)TNFRSF17 Origin: Cynomolgus, Rhesus Monkey Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17) (AA 1-54) (Active) protein (Biotin,His-Avi Tag)TNFRSF17 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE Active
Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17) (AA 1-49) (Active) protein (Biotin,His-Avi Tag)TNFRSF17 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE Active
Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17) (AA 1-54), (Trimer) (Active) protein (His-Avi Tag)TNFRSF17 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17) (AA 1-49) (Active) protein (His-Avi Tag)TNFRSF17 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE Active
Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17) (AA 1-54) (Active) protein (hFc Tag)TNFRSF17 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17) (AA 1-54) (Active) protein (Fc Tag)TNFRSF17 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17) (AA 1-54), (Trimer) (Active) protein (Biotin,His-Avi Tag)TNFRSF17 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE Active
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstitute with 50 μL sterile water.
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Concentration
- 1 mg/mL
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Buffer
- Contains PBS.
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Handling Advice
- After reconstitution, prepare aliquots and store at -20 °C. Avoid freeze/thaw cycles. Centrifuge lyophilized vial before opening and reconstitution. PBS containing at least 0.1 % BSA should be used for further dilutions.
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Storage
- 4 °C,-20 °C
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Storage Comment
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Short Term Storage: +4°C
Long Term Storage: -20°C
Use & Stability: Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
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Expiry Date
- 6 months
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- BCMA (TNFRSF17) (Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17))
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Alternative Name
- BCMA
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Background
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B Cell Maturation Protein, CD269, TNFRSF17
BCMA is a receptor for BAFF and APRIL. It promotes B cell survival and plays a role in the regulation of humoral immunity. It's downstream signaling is dependent on NF-kappaB and JNK.
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Molecular Weight
- ~35kDa (SDS-PAGE)
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UniProt
- O88472
Target
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