Bcl-2 Protein (AA 1-239) (GST tag)
Quick Overview for Bcl-2 Protein (AA 1-239) (GST tag) (ABIN1346542)
Target
See all Bcl-2 (BCL2) ProteinsProtein Type
Origin
Source
Application
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Protein Characteristics
- AA 1-239
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Purification tag / Conjugate
- This Bcl-2 protein is labelled with GST tag.
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Purpose
- BCL2 (Human) Recombinant Protein (P01)
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Sequence
- MAHAGRTGYD NREIVMKYIH YKLSQRGYEW DAGDVGAAPP GAAPAPGIFS SQPGHTPHPA ASRDPVARTS PLQTPAAPGA AAGPALSPVP PVVHLTLRQA GDDFSRRYRR DFAEMSSQLH LTPFTARGRF ATVVEELFRD GVNWGRIVAF FEFGGVMCVE SVNREMSPLV DNIALWMTEY LNRHLHTWIQ DNGGWDAFVE LYGPSMRPLF DFSWLSLKTL LSLALVGACI TLGAYLGHK
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Characteristics
- Human BCL2 full-length ORF ( AAH27258.1, 1 a.a. - 239 a.a.) recombinant protein with GST-tag at N-terminal.
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Purification
- in vitro wheat germ expression system
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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Preparation method: in vitro, wheat germ expression system
Product Quality tested by: 12.5% SDS-PAGE Stained with Coomassie Blue. -
Restrictions
- For Research Use only
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Buffer
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.
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Handling Advice
- Aliquot to avoid repeated freezing and thawing.
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Storage
- -80 °C
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Storage Comment
- Best use within three months from the date of receipt of this protein.
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: "Threonine 56 phosphorylation of Bcl-2 is required for LRRK2 G2019S-induced mitochondrial depolarization and autophagy." in: Biochimica et biophysica acta, Vol. 1852, Issue 1, pp. 12-21, (2014) (PubMed).
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- Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
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Alternative Name
- BCL2
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Background
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Full Gene Name: B-cell CLL/lymphoma 2
Synonyms: Bcl-2 -
Gene ID
- 596
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Pathways
- MAPK Signaling, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagy, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling
Target
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