p21 Protein (AA 2-164) (His tag)

Catalog No. ABIN1458670

Product Details

Target: p21 (CDKN1A) (Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A))

Protein Type: Recombinant

Protein Characteristics: AA 2-164

Origin: Cat

Source: Yeast

Purification tag / Conjugate: This p21 protein is labelled with His tag.

Application: ELISA

Sequence: SEPSRDAHQ IPHGSKACRR LFGPVDSEQL RRDCDALMAG CVQEARERWN FDFVTETPLE GDFAWERVWG LGLPKLYLPA GPRGGRDDLG GGKRPSTSST LLPGTAREDH LDLSLSCTLM PHSPERPEAS PGAPGTSQGR KRRQTSMTDF YHSKRRLIFS KRKP

Specificity: Felis catus (Cat) (Felis silvestris catus)

Characteristics: Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.

Purity: > 90 %

Application Details

Comment:

The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: 0.2-2 mg/mL

Buffer: Tris-based buffer, 50 % glycerol

Handling Advice: Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week

Storage: -20 °C

Storage Comment: Store at -20 °C, for extended storage, conserve at -20 °C or -80 °C.

Target Details

Target: p21 (CDKN1A) (Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A))

Alternative Name: Cyclin-dependent kinase inhibitor 1 (CDKN1A) (CDKN1A Products)

Background: Recommended name: Cyclin-dependent kinase inhibitor 1.
Alternative name(s): CDK-interacting protein 1 p21

UniProt: O19002

Pathways: p53 Signaling, PI3K-Akt Signaling, Cell Division Cycle, AMPK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Mitotic G1-G1/S Phases, DNA Replication, Hepatitis C, Synthesis of DNA, Autophagy