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IL17RC Protein (C-Term, Extracellular Domain)

This Recombinant IL17RC protein is expressed in HEK-293T Cells.
Catalog No. ABIN1684628

Quick Overview for IL17RC Protein (C-Term, Extracellular Domain) (ABIN1684628)

Target

See all IL17RC Proteins
IL17RC (Interleukin 17 Receptor C (IL17RC))

Protein Type

Recombinant

Origin

  • 10
  • 2
Human

Source

  • 5
  • 4
  • 1
  • 1
  • 1
HEK-293T Cells

Purity

> 98 %, as determined by SDS-PAGE and HPLC
  • Protein Characteristics

    C-Term, Extracellular Domain

    Specificity

    Optimized DNA sequence encoding extracellular domain of human IL-17RC receptor including a C terminal Human IgG1 Fc tag was expressed in HEK293 cells.

    Characteristics

    Recombinant IL17RC-Fc is a homodimer protein consisting of 675 amino acid residue subunits, due to glycosylation migrates as an approximately 100kD protein under reducing SDS-PAGE conditions.

    Sterility

    0.2 μm filtered

    Endotoxin Level

    Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg(1EU/µg).
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    PBS solution, pH7.2

    Handling Advice

    Avoid repeated freeze/thaw cycles.

    Storage

    -20 °C

    Storage Comment

    The lyophilized protein is stable for at least years from date of receipt at -20 °C. Upon reconstitution, this cytokine can be stored in working aliquots at - 8 °C for one month, or at -20 °C for six months, with a carrier protein without detectable loss of activity.

    Expiry Date

    12-24 months
  • Target

    IL17RC (Interleukin 17 Receptor C (IL17RC))

    Alternative Name

    IL17RC

    Background

    Common gamma chain Interleukin (IL)-2, IL-4, IL-7, IL-9 and IL-15 belong to a family of cytokines whose receptors share the common gamma chain (gamma c). Despite some redundancy, thesecytokines that signal through the gamma c (gamma c cytokines) have essentially distinct and oftencritical effects in normal T-cell development, survival, proliferation and differentiation. Importantly, they have also been implicated,directly or indirectly, in T-cell leukemogenesis.

    UniProt

    Q8NAC3
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