IL17RC Protein (Fc Tag)
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- Target See all IL17RC Proteins
- IL17RC (Interleukin 17 Receptor C (IL17RC))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This IL17RC protein is labelled with Fc Tag.
- Purpose
- Recombinant Human IL17RC Protein (Fc Tag)(Active)
- Sequence
- Met 1-Ala 454
- Characteristics
- A DNA sequence encoding the extracellular domain of human IL17RC isoform 3 (NP_116121.2) (Met 1-Ala 454) was fused with the Fc region of human IgG1 at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Biological Activity Comment
- Measured by its ability to bind with recombinant human IL17A-His in a functional ELISA.2. Measured by its ability to bind with recombinant human 17A in a functional ELISA.
- Top Product
- Discover our top product IL17RC Protein
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Interleukin 17 Receptor C (IL17RC) (AA 21-467) protein (Fc Tag)
IL17RC Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 17 Receptor C (IL17RC) (AA 21-465) (Active) protein (Fc Tag)IL17RC Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Interleukin 17 Receptor C (IL17RC) (AA 1-538) protein (GST tag)IL17RC Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, pH 7.4
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- IL17RC (Interleukin 17 Receptor C (IL17RC))
- Alternative Name
- IL17RC (IL17RC Products)
- Synonyms
- IL17-RL Protein, IL17RL Protein, 1110025H02Rik Protein, Gm19850 Protein, IL-17RC Protein, IL17-RC Protein, Il17rl Protein, interleukin 17 receptor C Protein, Il17rc Protein, IL17RC Protein
- Background
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Background: Plexin domain-containing protein 1; also known as tumor endothelial marker 3; tumor endothelial marker 7 and PLXDC1 and TEM3; is a secreted; cytoplasm and single-pass type I membrane protein which belongs to the plexin family. PLXDC1 / TEM3 is detected in endothelial cells from colorectal cancer; and in endothelial cells from primary cancers of the lung; liver; pancreas; breast and brain. It is expressed in fibrovascular membrane with increased expression in individuals with proliferative diabetic retinopathy. PLXDC1 / TEM3 is not detectable in endothelial cells from normal tissue. PLXDC1 / TEM3 plays a critical role in endothelial cell capillary morphogenesis. PLXDC1 / TEM3 may play a significant role in the proliferation and maintenance of neovascular endothelial cells in the formation of fibrovascular membranes (FVMs). PLXDC1 / TEM3 may be a molecular target for new diagnostic and therapeutic strategies for proliferative diabetic retinopathy (PDR). PLXDC1 / TEM3 interacts with NID1. It may also interact with CTTN.
Synonym: IL17-RL;IL17RL;UNQ6118/PRO20040/PRO38901
- Molecular Weight
- 75.3 kDa
- NCBI Accession
- NP_116121
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