IL17RC Protein (AA 257-477) (His tag)
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- Target See all IL17RC Proteins
- IL17RC (Interleukin 17 Receptor C (IL17RC))
- Biological Activity
- Active
- Protein Characteristics
- AA 257-477
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This IL17RC protein is labelled with His tag.
- Application
- Activity Assay (AcA), Cell Culture (CC)
- Characteristics
- Tag location: N-terminal His Tag
- Purity
- > 97 %
- Biological Activity Comment
- IL17RC (Interleukin-17 receptor C) is a receptor for IL17A and IL17F homodimers as part of a heterodimeric complex with IL17RA. This protein is expressed in nonhemopoietic tissues, and binds both IL-17A and IL-17F with similar affinities. A binding ELISA assay was conducted to detect the association of IL17RC with IL17RA. Briefly, IL17RC were diluted serially in PBS with 0.01%BSA (pH 7.4). Duplicate samples of 100uL were then transferred to IL17RA-coated microtiter wells and incubated for 2h at 37°C. Wells were washed with PBST and incubated for 1h with anti-IL17RC pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37°C. Finally, add 50μL stop solution to the wells and read at 450nm immediately. The binding activity of IL17RC with IL17RA was shown in Figure 1 and this effect was in a dose dependent manner The binding activity of IL17RC with IL17RA.
- Top Product
- Discover our top product IL17RC Protein
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- Application Notes
- Isoelectric Point: 5.8
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4, containing 0.01 % SKL, 1 mM DTT, 5 % Trehalose and Proclin300.
- Preservative
- Dithiothreitol (DTT), ProClin
- Precaution of Use
- This product contains ProClin and Dithiothreitol (DTT): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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- Target
- IL17RC (Interleukin 17 Receptor C (IL17RC))
- Abstract
- IL17RC Products
- Synonyms
- IL17-RL Protein, IL17RL Protein, 1110025H02Rik Protein, Gm19850 Protein, IL-17RC Protein, IL17-RC Protein, Il17rl Protein, interleukin 17 receptor C Protein, Il17rc Protein, IL17RC Protein
- Background
- Alternative Names: IL17-RL, IL17R-C, IL17Rhom, Interleukin-17 receptor homolog, Interleukin-17 receptor-like protein, ZcytoR14
- Molecular Weight
- 26kDa
- UniProt
- Q8NAC3
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