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EPOR Protein (C-Term, Extracellular Domain)

EPOR Origin: Mouse Host: HEK-293T Cells Recombinant > 97 %, as determined by SDS-PAGE and HPLC
Catalog No. ABIN1684690
  • Target See all EPOR Proteins
    EPOR (Erythropoietin Receptor (EPOR))
    Protein Type
    Recombinant
    Protein Characteristics
    C-Term, Extracellular Domain
    Origin
    • 18
    • 6
    • 2
    • 1
    • 1
    • 1
    Mouse
    Source
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    HEK-293T Cells
    Specificity
    Optimized DNA sequence encoding extracellular domain of mouse erythropoietin receptor including a C-terminal His tag was expressed in HEK293 cells.
    Characteristics
    Recombinant mouse EPO receptor is a monomer protein consisting of37 amino acid residue subunits, due to glycosylation migrates as an approximately 35 kDa protein on SDS-PAGE.
    Purity
    > 97 %, as determined by SDS-PAGE and HPLC
    Sterility
    0.2 μm filtered
    Endotoxin Level
    Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg(1EU/µg).
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    Discover our top product EPOR Protein
  • Restrictions
    For Research Use only
  • Buffer
    PBS solution, pH7.2
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    -20 °C
    Storage Comment
    The lyophilized protein is stable for at least years from date of receipt at -20 °C. Upon reconstitution, this cytokine can be stored in working aliquots at - 8 °C for one month, or at -20 °C for six months, with a carrier protein without detectable loss of activity.
    Expiry Date
    12-24 months
  • Target
    EPOR (Erythropoietin Receptor (EPOR))
    Alternative Name
    EPOR (EPOR Products)
    Synonyms
    EPOR Protein, epor Protein, EPO-R Protein, erythropoietin receptor Protein, erythropoietin receptor L homeolog Protein, EPOR Protein, epor Protein, Epor Protein, epor.L Protein
    Background
    Monocyte Chemoattractant Proteins 4 (MCP-4/CCL13) is member of a distinct, structurally-related subclass of CC chemokines. MCP-4/CCL13 is a major chemoattractants for eosinophils, basophils monocytes and T lymphocytes. The MCP protein family bind to specific G-protein-coupled receptors, initiating a signal cascade within the cell. Expression of MCP-4/CCL13 mRNA and protein is greater in the sputum, epithelium, submucosal inflammatory cells and bronchoalveolar lavage fluid of asthmatics than in healthy individuals. Involvement of MCPs has also been demonstrated in renal inflammation and atopic dermatitis and the expression of this protein is also correlated with enhanced inflammatory immune responses during immunotherapy
    UniProt
    P14753
    Pathways
    JAK-STAT Signaling
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