Ephrin A1 Protein (EFNA1) (AA 19-182) (His-Fc tag)

Catalog No. ABIN1691768

Recombinant Ephrin A1 protein expressed in Human Cells.

Quick Overview for Ephrin A1 Protein (EFNA1) (AA 19-182) (His-Fc tag) (ABIN1691768)

Target: Ephrin A1 (EFNA1)

Protein Type: Recombinant

Origin: Mouse

Source: Human Cells

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Protein Characteristics: AA 19-182

Purification tag / Conjugate: This Ephrin A1 protein is labelled with His-Fc tag.

Purpose: Recombinant Mouse Ephrin-A1/EFNA1 (C-Fc-6His)

Sequence: DRHIVFWNSS NPKFREEDYT VHVQLNDYLD IICPHYEDDS VADAAMERYT LYMVEHQEYV ACQPQSKDQV RWNCNRPSAK HGPEKLSEKF QRFTPFILGK EFKEGHSYYY ISKPIYHQES QCLKLKVTVN GKITHNPQAH VNPQEKRLQA DDPEVQVLHS IGYSVDDIEG RMDEPKSCDK THTCPPCPAP ELLGGPSVFL FPPKPKDTLM ISRTPEVTCV VVDVSHEDPE VKFNWYVDGV EVHNAKTKPR EEQYNSTYRV VSVLTVLHQD WLNGKEYKCK VSNKALPAPI EKTISKAKGQ PREPQVYTLP PSREEMTKNQ VSLTCLVKGF YPSDIAVEWE SNGQPENNYK TTPPVLDSDG SFFLYSKLTV DKSRWQQGNV FSCSVMHEAL HNHYTQKSLS LSPGKHHHHH H

Characteristics: Recombinant Mouse Ephrin-A1 is produced by our Mammalian expression system and the target gene encoding Asp19-Ser182 is expressed with a Fc, 6His tag at the C-terminus.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4.

Storage: 4 °C,-20 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 3 weeks

Target Details

Target: Ephrin A1 (EFNA1)

Alternative Name: Ephrin-A1/Efna1

Background: Alternative Names: EPH-related receptor tyrosine kinase ligand 1, Immediate early response protein B61,Epgl1, Epl1, Lerk1Recombinant Mouse Ephrin-A1/Efna1 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Asp19-Ser182) of Mouse Ephrin-A1 fused with a FC-6His tag at the C-terminus.
Ephrin-A1 is a cell membrane protein and contains 1 ephrin RBD (ephrin receptor-binding) domain. EFNA1 belongs to the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNA class ephrin which binds to the EPHA2, EPHA4, EPHA5, EPHA6, and EPHA7 receptors. Two transcript variants that encode different isoforms were identified through sequence analysis.It belongs to the ephrin family and contains 1 ephrin RBD (ephrin receptor-binding) domain.

Molecular Weight: 47.3 kDa

UniProt: P52793

Pathways: RTK Signaling