FABP Heart (Active) Protein
Quick Overview for FABP Heart (Active) Protein (ABIN1880337)
Target
Protein Type
Biological Activity
Origin
Source
Application
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Purification
- Purified
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- 10 mM PBS( pH 7.4).
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Shipat 4°C.Upon receipt, aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze and thaw cycles.
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- FABP Heart
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Background
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Synonyms: Fattyacid-binding protein 3, FABP3, Heart-type fatty acid-binding protein, H-FABP, Mammary-derived growth inhibitor, MDGI, Muscle fatty acid-binding protein, M-FABP, FABP11
Description: Purified human FABP3 protein.
Background: Heart-type fatty acid binding protein (hFABP) also known as mammary-derived growth inhibitor is a protein that in humans is encoded by the FABP3 gene. It is a small cytoplasmic protein (15 kDa) released from cardiac myocytes following an ischemic episode. Like the nine other distinct FABPs that have been identified, H-FABP is involved in active fatty acid metabolism where it transports fatty acids from the cell membrane to mitochondria for oxidation. H-FABP is a sensitive biomarker for myocardial infarction and can be detected in the blood within one to three hours of the pain. It is also the biomarker for heart injury. In addition to its diagnostic potential, H-FABP also has prognostic value. Alongside D-dimer, NT-proBNP and peak troponin T, it was the only cardiac biomarker that proved to be a statistically significant predictor of death or Mi at one year.
Target
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