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FABP Heart Protein

This Recombinant FABP Heart protein is produced in Escherichia coli (E. coli).
Catalog No. ABIN1880369
$594.00
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 11 to 13 Business Days

Quick Overview for FABP Heart Protein (ABIN1880369)

Target

FABP Heart

Protein Type

Recombinant

Origin

Human

Source

  • 1
Escherichia coli (E. coli)

Purity

> 95 % by SDS-PAGE
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  • Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    20 mM Tris-HCL, 140 mM NaCl, 2 mM EDTA (pH 8.0)

    Preservative

    Without preservative

    Storage

    4 °C
  • Target

    FABP Heart

    Background

    Heart-type fatty acid binding protein (hFABP) also known as mammary-derived growth inhibitor is a protein that in humans is encoded by the FABP3 gene. It is a small cytoplasmic protein (15 kDa) released from cardiac myocytes following an ischemic episode. Like the nine other distinct FABPs that have been identified, H-FABP is involved in active fatty acid metabolism where it transports fatty acids from the cell membrane to mitochondria for oxidation. H-FABP is a sensitive biomarker for myocardial infarction and can be detected in the blood within one to three hours of the pain. It is also the biomarker for heart injury. In addition to its diagnostic potential, H-FABP also has prognostic value. Alongside D-dimer, NT-proBNP and peak troponin T, it was the only cardiac biomarker that proved to be a statistically significant predictor of death or Mi at one year.

    Molecular Weight

    15 kDa
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