S100A1B (Active) Protein

Catalog No. ABIN1880350

Native S100A1B protein expressed in Human.

Quick Overview for S100A1B (Active) Protein (ABIN1880350)

Target: S100A1B

Protein Type: Native

Biological Activity: Active

Origin: Human

Source: Human

Application: ELISA

Product Details

Purification: Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 10 mM PBS( pH 7.4).

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Shipat 4°C.Upon receipt, aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze and thaw cycles.

Target Details

Target: S100A1B

Background:

Description: Purified human S100A1B protein.

Background: S100 proteins, such as S100A1 (S100 calcium-binding protein A1), are small, acidic Ca(2+)-binding proteins that transduce Ca(2+) signals via interaction with intracellular target proteins. The protein encoded by this gene is a member of the S100 family of proteins containing 4 EF-hand calcium-binding motifs in its dimerized form. S100A1 is preferentially expressed in myocardial tissue and has been found to colocalize with the sarcoplasmic reticulum (SR) and the contractile filaments in cardiac tissue. Its overexpression enhances cardiac contractile performance and establish the concept of S100A1 as a regulator of myocardial contractility. S100A1 thus improves cardiac contractile performance both by regulating SR Ca(2+) handling and myofibrillar Ca(2+) responsiveness.