S100A1B (Active) Protein
Quick Overview for S100A1B (Active) Protein (ABIN1880438)
Target
Protein Type
Biological Activity
Origin
Source
Application
Purity
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Tris-HCl( pH 7.4±0.2) with 0.1 % Sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Shipat 4°C. Upon receipt, aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze and thaw cycles.
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- S100A1B
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Background
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Description: Recombinant full length human S100A1B protein with molecular weight 22 kDa.
Background: S100 proteins, such as S100A1 (S100 calcium-binding protein A1), are small, acidic Ca(2+)-binding proteins that transduce Ca(2+) signals via interaction with intracellular target proteins. The protein encoded by this gene is a member of the S100 family of proteins containing 4 EF-hand calcium-binding motifs in its dimerized form. S100A1 is preferentially expressed in myocardial tissue and has been found to colocalize with the sarcoplasmic reticulum (SR) and the contractile filaments in cardiac tissue. Its overexpression enhances cardiac contractile performance and establish the concept of S100A1 as a regulator of myocardial contractility. S100A1 thus improves cardiac contractile performance both by regulating SR Ca(2+) handling and myofibrillar Ca(2+) responsiveness.
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Molecular Weight
- 22 kDa
Target
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