CTSA Protein (AA 29-480) (His tag)

Catalog No. ABIN1945628

Recombinant CTSA protein expressed in Human Cells.

Quick Overview for CTSA Protein (AA 29-480) (His tag) (ABIN1945628)

Target: CTSA (Cathepsin A (CTSA))

Protein Type: Recombinant

Origin: Human

Source: Human Cells

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Protein Characteristics: AA 29-480

Purification tag / Conjugate: This CTSA protein is labelled with His tag.

Purpose: Recombinant Human Cathepsin A/CTSA (C-6His)

Sequence: APDQDEIQRL PGLAKQPSFR QYSGYLKGSG SKHLHYWFVE SQKDPENSPV VLWLNGGPGC SSLDGLLTEH GPFLVQPDGV TLEYNPYSWN LIANVLYLES PAGVGFSYSD DKFYATNDTE VAQSNFEALQ DFFRLFPEYK NNKLFLTGES YAGIYIPTLA VLVMQDPSMN LQGLAVGNGL SSYEQNDNSL VYFAYYHGLL GNRLWSSLQT HCCSQNKCNF YDNKDLECVT NLQEVARIVG NSGLNIYNLY APCAGGVPSH FRYEKDTVVV QDLGNIFTRL PLKRMWHQAL LRSGDKVRMD PPCTNTTAAS TYLNNPYVRK ALNIPEQLPQ WDMCNFLVNL QYRRLYRSMN SQYLKLLSSQ KYQILLYNGD VDMACNFMGD EWFVDSLNQK MEVQRRPWLV KYGDSGEQIA GFVKEFSHIA FLTIKGAGHM VPTDKPLAAF TMFSRFLNKQ PYHHHHHH

Characteristics: Recombinant Human Cathepsin A is produced by our Mammalian expression system and the target gene encoding Ala29-Tyr480 is expressed with a 6His tag at the C-terminus.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 um filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

Handling Advice: minimize freeze-thaw cycles

Storage: -20 °C

Storage Comment: Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.

Expiry Date: 6 months

Target Details

Target: CTSA (Cathepsin A (CTSA))

Alternative Name: Cathepsin A

Background: Alternative Names: Lysosomal protective protein,CTSA,Carboxypeptidase C,Carboxypeptidase L,Cathepsin ACathepsin A is active in cellular compartments called lysosomes. These compartments contain enzymes that digest and recycle materials when they are no longer needed. Cathepsin A interacts with the enzymes β-galactosidase and neuraminidase 1, which play a role in the breakdown of complexes of sugar molecules (oligosaccharides) attached to certain proteins (glycoproteins) or fats (glycolipids). Cathepsin A forms a complex with these two enzymes and directs their transport within the cell to the lysosomes. Within lysosomes, cathepsin A activates the enzymes and prevents their breakdown.

Molecular Weight: 52.2 kDa

UniProt: P10619