Desmin Protein (DES) (AA 1-470) (GST tag)
Quick Overview for Desmin Protein (DES) (AA 1-470) (GST tag) (ABIN1989616)
Target
See all Desmin (DES) ProteinsProtein Type
Origin
Source
Application
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Protein Characteristics
- AA 1-470
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Purification tag / Conjugate
- This Desmin protein is labelled with GST tag.
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Purpose
- DES (Human) Recombinant Protein (P01)
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Sequence
- MSQAYSSSQR VSSYRRTFGG APGFPLGSPL SSPVFPRAGF GSKGSSSSVT SRVYQVSRTS GGAGGLGSLR ASRLGTTRTP SSYGAGELLD FSLADAVNQE FLTTRTNEKV ELQELNDRFA NYIEKVRFLE QQNAALAAEV NRLKGREPTR VAELYEEELR ELRRQVEVLT NQRARVDVER DNLLDDLQRL KAKLQEEIQL KEEAENNLAA FRADVDAATL ARIDLERRIE SLNEEIAFLK KVHEEEIREL QAQLQEQQVQ VEMDMSKPDL TAALRDIRAQ YETIAAKNIS EAEEWYKSKV SDLTQAANKN NDALRQAKQE MMEYRHQIQS YTCEIDALKG TNDSLMRQMR ELEDRFASEA SGYQDNIARL EEEIRHLKDE MARHLREYQD LLNVKMALDV EIATYRKLLE GEESRINLPI QTYSALNFRE TSPEQRGSEV HTKKTVMIKT IETRDGEVVS EATQQQHEVL
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Characteristics
- Human DES full-length ORF (AAH32116.1, 1 a.a. - 470 a.a.) recombinant protein with GST tag at N-terminal.
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Purification
- in vitro wheat germ expression system
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Buffer
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.
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Handling Advice
- Aliquot to avoid repeated freezing and thawing.
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Storage
- -80 °C
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Storage Comment
- Best use within three months from the date of receipt of this protein.
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- Desmin (DES)
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Alternative Name
- DES
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Background
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Synonyms: CMD1I,CSM1,CSM2,FLJ12025,FLJ39719,FLJ41013,FLJ41793
Gene Description: desmin
Gene Name: DES
Gene Summary: This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.
GenBank: BC032116.2, AAH32116.1 -
Molecular Weight
- 79.9 kDa (theoreatical)
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Gene ID
- 1674
Target
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