IL-5 Protein (AA 21-133)
Quick Overview for IL-5 Protein (AA 21-133) (ABIN2018026)
Target
See all IL-5 (IL5) ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Protein Characteristics
- AA 21-133
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Characteristics
- ED50 < 0.5 ng/mL, measured in a cell proliferation assay using TF-1 cells, corresponding to a specific activity of > 2x10^6 units/mg.
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Endotoxin Level
- < 0.2 EU/μg, determined by LAL method.
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Interleukin 5 (IL5) (AA 20-134) protein (His-Avi Tag)
IL5 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 5 (IL5) (AA 20-134) protein (His-Avi Tag,Biotin)IL5 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 5 (IL5) (AA 21-133) protein (His-Avi Tag)IL5 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Interleukin 5 (IL5) (AA 20-134) protein (His tag)IL5 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 5 (IL5) (AA 20-134) protein (His tag)IL5 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Interleukin 5 (IL5) (AA 20-134) protein (Fc Tag)IL5 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Interleukin 5 (IL5) (AA 21-133) protein (His-Avi Tag,Biotin)IL5 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 5 (IL5) protein (mFc Tag)IL5 Origin: Human Host: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE.
Interleukin 5 (IL5) protein (His tag)IL5 Origin: Mouse Host: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE.
Interleukin 5 (IL5) (AA 20-132) protein (His tag)IL5 Origin: Rat Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
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Buffer
- Lyophilized after extensive dialysis against PBS.
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Storage
- -80 °C
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Storage Comment
- Lyophilized recombinant Murine Interlerkin 5 (IL-5) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rmIL-5 should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
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Expiry Date
- 6 months
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- IL-5 (IL5) (Interleukin 5 (IL5))
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Alternative Name
- Interleukin 5 (IL-5)
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Background
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Interleukin-5 (IL-5), produced by mast cells, T cells and eosinophils, is responsible for the activities attributed to eosinophil differentiating factor, B cell growth factor II and T cell-replacing factor (TRF). It can increase production and mobilization of eosinophils and CD34+ progenitors from the bone marrow. IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. IL-5 also promotes differentiation of basophils and primes them for histamine and leukotriene release.Recombinant Murine IL-5 is homodimeric protein with molecular weight ranging from 25 to 40 kDa due to glycosylation.
Synonyms: EDF, BCDFII, TRF -
Molecular Weight
- 25-40 kDa, observed by non-reducing SDS-PAGE.
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UniProt
- P04401
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Pathways
- JAK-STAT Signaling, Positive Regulation of Peptide Hormone Secretion, Production of Molecular Mediator of Immune Response, Feeding Behaviour
Target
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