IL-5 Protein (AA 21-133) (His-Avi Tag)
-
- Target See all IL-5 (IL5) Proteins
- IL-5 (IL5) (Interleukin 5 (IL5))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 21-133
-
Origin
- Mouse
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This IL-5 protein is labelled with His-Avi Tag.
- Purpose
- Mouse IL-5 Protein
- Sequence
- Met21-Gly133
- Characteristics
- Recombinant Mouse IL-5 Protein is expressed from HEK293 with His tag and Avi tag at the N-Terminus.It contains Met21-Gly133.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- The affinity constant of 0.495 μM as determined in SPR assay (Biacore T200). See testing image for detail.
- Top Product
- Discover our top product IL5 Protein
-
-
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- Supplied as 0.22μm filtered solution in 20 mM Tris, 500 mM NaCl, 10 % Glycerol ( pH 7.0).
- Storage
- -80 °C
- Storage Comment
- Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
-
- Target
- IL-5 (IL5) (Interleukin 5 (IL5))
- Alternative Name
- IL-5 (IL5 Products)
- Synonyms
- EDF Protein, IL-5 Protein, TRF Protein, Il-5 Protein, IL5 Protein, interleukin 5 Protein, IL5 Protein, Il5 Protein
- Background
- IL-5 is an important cytokine for priming and survival of mature eosinophils and for proliferation and maturation of their progenitors. IL-5(Rα) targeting will be increasingly used in diseases where eosinophils are the key immune effector cells such as eosinophilic asthma (EA), hypereosinophilic syndrome (HES), eosinophilic esophagitis (EE), and eosinophilic granulomatosis with polyangiitis (EGPA).
- Molecular Weight
- 16.03 kDa. Due to glycosylation, the protein migrates to 16.03 kDa and 20-32 kDa based on Tris-Bis PAGE result.
- UniProt
- P04401
- Pathways
- JAK-STAT Signaling, Positive Regulation of Peptide Hormone Secretion, Production of Molecular Mediator of Immune Response, Feeding Behaviour
-