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IL-5 Protein (AA 21-133) (His-Avi Tag,Biotin)

IL5 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Catalog No. ABIN7274960
  • Target See all IL-5 (IL5) Proteins
    IL-5 (IL5) (Interleukin 5 (IL5))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 21-133
    Origin
    • 20
    • 14
    • 7
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Mouse
    Source
    • 27
    • 16
    • 9
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This IL-5 protein is labelled with His-Avi Tag,Biotin.
    Purpose
    Biotinylated Mouse IL-5 Protein
    Sequence
    Met21-Gly133
    Characteristics
    Recombinant Biotinylated Mouse IL-5 Protein is expressed from HEK293 with His tag and Avi tag at the N-Terminus.It contains Met21-Gly133.
    Purity
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    The affinity constant of 0.511 μM as determined in SPR assay (Biacore T200). See testing image for detail.
    Top Product
    Discover our top product IL5 Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Supplied as 0.22μm filtered solution in 20 mM Tris, 500 mM NaCl, 10 % Glycerol ( pH 7.0).
    Storage
    -80 °C
    Storage Comment
    Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    IL-5 (IL5) (Interleukin 5 (IL5))
    Alternative Name
    IL-5 (IL5 Products)
    Synonyms
    EDF Protein, IL-5 Protein, TRF Protein, Il-5 Protein, IL5 Protein, interleukin 5 Protein, IL5 Protein, Il5 Protein
    Background
    IL-5 is an important cytokine for priming and survival of mature eosinophils and for proliferation and maturation of their progenitors. IL-5(Rα) targeting will be increasingly used in diseases where eosinophils are the key immune effector cells such as eosinophilic asthma (EA), hypereosinophilic syndrome (HES), eosinophilic esophagitis (EE), and eosinophilic granulomatosis with polyangiitis (EGPA).
    Molecular Weight
    16.0 kDa. Due to glycosylation, the protein migrates to 16 kDa and 20-35 kDa based on Tris-Bis PAGE result.
    UniProt
    P04401
    Pathways
    JAK-STAT Signaling, Positive Regulation of Peptide Hormone Secretion, Production of Molecular Mediator of Immune Response, Feeding Behaviour
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