IL-5 Protein (AA 21-133)
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- Target See all IL-5 (IL5) Proteins
- IL-5 (IL5) (Interleukin 5 (IL5))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 21-133
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Origin
- Mouse
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Source
- CHO Cells
- Characteristics
- ED50 < 0.5 ng/mL, measured in a cell proliferation assay using TF-1 cells, corresponding to a specific activity of > 2x10^6 units/mg.
- Purity
- > 95 % as analyzed by SDS-PAGE and HPLC.
- Endotoxin Level
- < 0.2 EU/μg, determined by LAL method.
- Top Product
- Discover our top product IL5 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
- Buffer
- Lyophilized after extensive dialysis against PBS.
- Storage
- -80 °C
- Storage Comment
- Lyophilized recombinant Murine Interlerkin 5 (IL-5) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rmIL-5 should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
- Expiry Date
- 6 months
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- Target
- IL-5 (IL5) (Interleukin 5 (IL5))
- Alternative Name
- Interleukin 5 (IL-5) (IL5 Products)
- Synonyms
- EDF Protein, IL-5 Protein, TRF Protein, Il-5 Protein, IL5 Protein, interleukin 5 Protein, IL5 Protein, Il5 Protein
- Background
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Interleukin-5 (IL-5), produced by mast cells, T cells and eosinophils, is responsible for the activities attributed to eosinophil differentiating factor, B cell growth factor II and T cell-replacing factor (TRF). It can increase production and mobilization of eosinophils and CD34+ progenitors from the bone marrow. IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. IL-5 also promotes differentiation of basophils and primes them for histamine and leukotriene release.Recombinant Murine IL-5 is homodimeric protein with molecular weight ranging from 25 to 40 kDa due to glycosylation.
Synonyms: EDF, BCDFII, TRF - Molecular Weight
- 25-40 kDa, observed by non-reducing SDS-PAGE.
- UniProt
- P04401
- Pathways
- JAK-STAT Signaling, Positive Regulation of Peptide Hormone Secretion, Production of Molecular Mediator of Immune Response, Feeding Behaviour
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