IL-10 Protein (AA 19-178)
Quick Overview for IL-10 Protein (AA 19-178) (ABIN2018045)
Target
See all IL-10 (IL10) ProteinsProtein Type
Biological Activity
Origin
Source
Purity
-
-
Protein Characteristics
- AA 19-178
-
Characteristics
- ED50 <0.2 ng/mL, measured in a cell proliferation assay using MC/9 cells.
-
Endotoxin Level
- < 0.2 EU/μg, determined by LAL method.
-
-
Want other Options for this Protein ?
!Discover Our Predefined Custom Proteins and Custom Protein Services!Your project requires further customization? Contact us and discover our custom protein solutions
-
Interleukin 10 (IL10) (AA 19-178) protein
IL10 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 10 (IL10) (AA 19-178) (Active) proteinIL10 Origin: Human Host: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE and HPLC. Active
Interleukin 10 (IL10) (AA 19-178) protein (His-Avi Tag)IL10 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 10 (IL10) (AA 19-178) protein (His-Avi Tag,Biotin)IL10 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Interleukin 10 (IL10) (Active) proteinIL10 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Interleukin 10 (IL10) (AA 22-178) protein (His tag)IL10 Origin: Hamster Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Interleukin 10 (IL10) (AA 1-178) protein (GST tag)IL10 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Interleukin 10 (IL10) proteinIL10 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE
Interleukin 10 (IL10) (AA 19-178) protein (His tag)IL10 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
-
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
-
Buffer
- Lyophilized after extensive dialysis against PBS.
-
Storage
- -80 °C
-
Storage Comment
- Lyophilized recombinant murine Interleukin-10 remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, murine Interleukin-10 should be stable up to 1 week at 4°C or up to 2 months at -20°C.
-
Expiry Date
- 6 months
-
-
- IL-10 (IL10) (Interleukin 10 (IL10))
-
Alternative Name
- Interleukin-10 (IL-10)
-
Background
-
Interleukin-10 (IL-10), initially known as Cytokine Synthesis Inhibitory Factor (CSIF), belongs to the IL-10 family and shares more than 80 % sequence homology with the Epstein-Barr Virus protein BCRFI. It is produced by many immune cells, such as T-cells, macrophages, mast cells and dendritic cells. It is usually secreted as a homodimer and, upon binding to its receptor, inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF, by activated macrophages and Th2 cells. It also displays the ability to suppress Antigen-Presenting Cell (APC) function. The net effect of Interleukin-10 appears to be inhibitory, however, stimulatory effects, such as stimulation of B cell maturation and antibody production, are also reported.
Synonyms: B-TCGF, CSIF, TGIF -
Molecular Weight
- 21-23 kDa, observed by reducing SDS-PAGE.
-
UniProt
- P18893
-
Pathways
- Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location, Cancer Immune Checkpoints
Target
-
