IL-22 Protein (AA 34-179)
Quick Overview for IL-22 Protein (AA 34-179) (ABIN2018097)
Target
See all IL-22 (IL22) ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Protein Characteristics
- AA 34-179
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Characteristics
- Active, measured by its ability to activate STAT following receptor ligand interaction.
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Endotoxin Level
- < 0.2 EU/μg, determined by LAL method.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
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Buffer
- Lyophilized after extensive dialysis against PBS.
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Storage
- -80 °C
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Storage Comment
- Lyophilized recombinant Human Interleukin-22 (IL-22) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Human Interleukin-22 (IL-22) should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
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Expiry Date
- 6 months
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- IL-22 (IL22) (Interleukin 22 (IL22))
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Alternative Name
- Interleukin-22 (IL-22)
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Background
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Interleukin-22 (IL-22) is a member of the IL-10 family of regulatory cytokines which includes IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. Members of this family share partial homology in their amino acid sequences, but they are dissimilar in their biological functions. Produced by T lymphocytes, IL-22 inhibits IL-4 production by Th2 cells, and induces acute phase reactants in the liver and pancreas. IL-22 signals through a receptor system consisting of IL-10R- /CRF2-4 and IL-22R, both of which are members of the class II cytokine-receptor family.
Synonyms: IL-TIF -
Molecular Weight
- 16-28 kDa, observed by reducing SDS-PAGE.
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NCBI Accession
- NP_065386
Target
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