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NGFR Protein (AA 29-250)

NGFR Origin: Human Host: HEK-293T Cells Recombinant > 95 % as analyzed by SDS-PAGE. Active
Catalog No. ABIN2018287
  • Target See all NGFR Proteins
    NGFR (Nerve Growth Factor Receptor (NGFR))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Protein Characteristics
    AA 29-250
    Origin
    • 6
    • 6
    • 2
    • 1
    Human
    Source
    • 3
    • 3
    • 3
    • 2
    • 2
    HEK-293T Cells
    Characteristics
    ED50 < 0.4 μg /mL, measured in a neutrolization assay using TF-1 cells in the presence of 10 ng/mL human b-NGF.
    Purity
    > 95 % as analyzed by SDS-PAGE.
    Endotoxin Level
    < 0.2 EU/μg, determined by LAL method.
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  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstituted in ddH2O or PBS at 100 μg/mL.
    Buffer
    Lyophilized after extensive dialysis against PBS.
    Storage
    -80 °C
    Storage Comment
    Lyophilized recombinant human NGF Receptor remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, human NGF Receptor should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
    Expiry Date
    6 months
  • Target
    NGFR (Nerve Growth Factor Receptor (NGFR))
    Alternative Name
    NGF Receptor (NGFR Products)
    Synonyms
    ngfr Protein, wu:fb38c02 Protein, wu:fc10h01 Protein, CD271 Protein, Gp80-LNGFR Protein, TNFRSF16 Protein, p75(NTR) Protein, p75NTR Protein, LNGFR Protein, RNNGFRR Protein, Tnfrsf16 Protein, p75 Protein, NRH1b Protein, fullback Protein, nrh1 Protein, p75ntr Protein, tnfrsf16 Protein, p75NGFR Protein, nerve growth factor receptor Protein, neurotrophin receptor associated death domain Protein, nerve growth factor receptor S homeolog Protein, nerve growth factor receptor (TNFR superfamily, member 16) Protein, NGFR Protein, nradd Protein, Ngfr Protein, ngfr.S Protein
    Background
    NGF Receptor, also known as Gp80-LNGFR, p75 ICD, CD271 and TNFRSF16, is a type I transmembrane protein belonging to the TNF receptor family. It is expressed by both neuronal and non-neuronal cells. Signaling through NGF Receptor has been shown to regulate gene expression, cell migration and death. A truncated NGF Receptor containing only the extracellular domain has been detected in plasma, amniotic fluid and urine, and acts as a potent NGF antagonist.
    Synonyms: Gp80-LNGFR, p75 ICD, CD271, TNFRSF16
    Molecular Weight
    32-60 kDa, observed by reducing SDS-PAGE.
    UniProt
    P08138
    Pathways
    NF-kappaB Signaling, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding
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