NGFR Protein (AA 29-250)
Quick Overview for NGFR Protein (AA 29-250) (ABIN2018287)
Target
See all NGFR ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Protein Characteristics
- AA 29-250
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Characteristics
- ED50 < 0.4 μg /mL, measured in a neutrolization assay using TF-1 cells in the presence of 10 ng/mL human b-NGF.
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Endotoxin Level
- < 0.2 EU/μg, determined by LAL method.
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Nerve Growth Factor Receptor (NGFR) (AA 1-427) protein (GST tag)
NGFR Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Nerve Growth Factor Receptor (NGFR) protein (His tag)NGFR Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE
Nerve Growth Factor Receptor (NGFR) (Active) protein (Fc Tag)NGFR Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE Active
Nerve Growth Factor Receptor (NGFR) protein (Myc-DYKDDDDK Tag)NGFR Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
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Buffer
- Lyophilized after extensive dialysis against PBS.
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Storage
- -80 °C
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Storage Comment
- Lyophilized recombinant human NGF Receptor remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, human NGF Receptor should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
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Expiry Date
- 6 months
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- NGFR (Nerve Growth Factor Receptor (NGFR))
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Alternative Name
- NGF Receptor
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Background
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NGF Receptor, also known as Gp80-LNGFR, p75 ICD, CD271 and TNFRSF16, is a type I transmembrane protein belonging to the TNF receptor family. It is expressed by both neuronal and non-neuronal cells. Signaling through NGF Receptor has been shown to regulate gene expression, cell migration and death. A truncated NGF Receptor containing only the extracellular domain has been detected in plasma, amniotic fluid and urine, and acts as a potent NGF antagonist.
Synonyms: Gp80-LNGFR, p75 ICD, CD271, TNFRSF16 -
Molecular Weight
- 32-60 kDa, observed by reducing SDS-PAGE.
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UniProt
- P08138
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Pathways
- NF-kappaB Signaling, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding
Target
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