VEGF 165 (AA 27-190) (Active) Protein
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- Target
- VEGF 165
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 27-190
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Origin
- Rat
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Source
- CHO Cells
- Characteristics
- ED50 < 4 ng/mL, measured in a cell proliferation assay using HUVEC cells, corresponding to a specific activity of >2.5 x 10^5 units/mg
- Purity
- > 95 % as analyzed by SDS-PAGE and HPLC.
- Endotoxin Level
- < 0.2 EU/μg, determined by LAL method.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
- Buffer
- Lyophilized after extensive dialysis against PBS.
- Storage
- -80 °C
- Storage Comment
- Lyophilized recombinant Rat Vascular Endothelial Growth Factor 165 (VEGF165) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rrVEGF165 should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
- Expiry Date
- 6 months
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- Target
- VEGF 165
- Alternative Name
- Vascular Endothelial Growth Factor 165 (VEGF165)
- Background
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Vascular Endothelial Growth Factor (VEGF) is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, Vascular Endothelial Growth Factor (VEGF) plays a prominent role in normal and pathological angiogenesis. Substantial evidence implicates Vascular Endothelial Growth Factor (VEGF) in the induction of tumor metastasis and intra-ocular neovascular syndromes. Vascular Endothelial Growth Factor (VEGF) signals through the three receptors, fms-like tyrosine kinase (flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product.
Synonyms: Vascular Endothelial Growth Factor, VPF, Folliculostellate cell-derived growth factor, Glioma-derived endothelial cell mitogen - Molecular Weight
- 35-48 kDa, observed by non-reducing SDS-PAGE.
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